-
公开(公告)号：EP2231216A2
公开(公告)日：2010-09-29
申请号：EP08862659.3
申请日：2008-12-12
发明人： CLARKE, John T. , O'CONNOR, Tim , XU, Yixin , O'BRIEN, Barry , ARCAND, Ben , SHIPPY, James Lee, III , ATANASOSKA, Liliana , FLANAGAN, Aiden , MCMORROW, Dave , WEBER, Jan , KREMER, John , KUEHLING, Michael , SEIDEL, Dominique
CPC分类号： A61L31/088 , A61L31/16 , A61L2300/45 , A61L2300/61
摘要： A drug-eluting endoprosthesis that includes a bioerodible metal portion and a therapeutic agent. In some aspects, the endoprosthesis includes a plurality of discrete deposits and a plurality of overlying layers each overlying one of the plurality of discrete deposits. Each discrete deposit includes one or more therapeutic agents and each overlying layer includes one or more bioerodible metals. In other aspects, the bioerodible metal portion includes at least two bioerodible metal regions having different electronegativities. The at least two bioerodible metal regions being in electrical contact with each other. The bioerodible metal erodes in a physiological environment to release the therapeutic agent.
-
公开(公告)号：EP2231216B1
公开(公告)日：2012-08-08
申请号：EP08862659.3
申请日：2008-12-12
发明人： CLARKE, John T. , O'CONNOR, Tim , XU, Yixin , O'BRIEN, Barry , ARCAND, Ben , SHIPPY, James Lee, III , ATANASOSKA, Liliana , FLANAGAN, Aiden , MCMORROW, Dave , WEBER, Jan , KREMER, John , KUEHLING, Michael , SEIDEL, Dominique
CPC分类号： A61L31/088 , A61L31/16 , A61L2300/45 , A61L2300/61
摘要： A drug-eluting endoprosthesis that includes a bioerodible metal portion and a therapeutic agent. In some aspects, the endoprosthesis includes a plurality of discrete deposits and a plurality of overlying layers each overlying one of the plurality of discrete deposits. Each discrete deposit includes one or more therapeutic agents and each overlying layer includes one or more bioerodible metals. In other aspects, the bioerodible metal portion includes at least two bioerodible metal regions having different electronegativities. The at least two bioerodible metal regions being in electrical contact with each other. The bioerodible metal erodes in a physiological environment to release the therapeutic agent.
-
搜索结果
2 条记录 (耗时 0.01 秒)
