公开(公告)号：EP4168492A1

公开(公告)日：2023-04-26

申请号：EP21734340.9

申请日：2021-06-22

申请人： Bracco Imaging SPA

发明人： BLASI, Francesco ,  BUONSANTI, Federica ,  CRIVELLIN, Federico ,  FERRARIS, Andrea ,  ORIO, Laura ,  PIZZUTO, Lorena ,  NAPOLITANO, Roberta ,  VALBUSA, Giovanni

IPC分类号： C09B23/01 ,  A61K49/00 ,  G01N33/533 ,  G01N33/58

公开(公告)号：EP4234634A3

公开(公告)日：2023-10-04

申请号：EP23168594.2

申请日：2020-05-12

申请人： Bracco Imaging SPA

发明人： BLASI, Francesco ,  BRIOSCHI, Chiara ,  BUONSANTI, Federica ,  MIRAGOLI, LUIGI ,  NAPOLITANO, Roberta ,  ORIO, Laura ,  PIZZUTO, Lorena ,  VALBUSA, Giovanni

IPC分类号： A61K49/00 ,  C07D471/18 ,  A61K39/00 ,  C07K7/52 ,  C07K16/28 ,  C07D209/14 ,  C07D403/12 ,  C07D417/14 ,  C09B23/08 ,  C09B23/06

摘要： The present invention relates to the field of optical imaging. More particularly, it relates to compounds of the cyanine family characterized by improved physico-chemical and biological properties and to their conjugates with biological ligands thereof. The invention also relates to the use of these compounds as optical diagnostic agents in imaging or therapy of solid tumors, to the methods for their preparation and to the compositions comprising them.

公开(公告)号：EP4188912A1

公开(公告)日：2023-06-07

申请号：EP21752511.2

申请日：2021-07-26

申请人： Bracco Imaging SPA

发明人： BARALE, Andrea ,  BOI, Valeria ,  FERRIGATO, Aurelia ,  GAZZETTO, Sonia ,  GIARDINA-PAPA, Daniela ,  MORTILLARO, Armando ,  ORIO, Laura ,  VERANI, Massimo

IPC分类号： C07D257/02

公开(公告)号：EP4234634A2

公开(公告)日：2023-08-30

申请号：EP23168594.2

申请日：2020-05-12

申请人： Bracco Imaging SPA

发明人： BLASI, Francesco ,  BRIOSCHI, Chiara ,  BUONSANTI, Federica ,  MIRAGOLI, LUIGI ,  NAPOLITANO, Roberta ,  ORIO, Laura ,  PIZZUTO, Lorena ,  VALBUSA, Giovanni

IPC分类号： C09B23/08

摘要： The present invention relates to the field of optical imaging. More particularly, it relates to compounds of the cyanine family characterized by improved physico-chemical and biological properties and to their conjugates with biological ligands thereof. The invention also relates to the use of these compounds as optical diagnostic agents in imaging or therapy of solid tumors, to the methods for their preparation and to the compositions comprising them.

公开(公告)号：EP3969063A1

公开(公告)日：2022-03-23

申请号：EP20723888.2

申请日：2020-05-12

申请人： Bracco Imaging SPA

发明人： BLASI, Francesco ,  BRIOSCHI, Chiara ,  BUONSANTI, Federica ,  MIRAGOLI, Luigi ,  NAPOLITANO, Roberta ,  ORIO, Laura ,  PIZZUTO, Lorena ,  VALBUSA, Giovanni

IPC分类号： A61K49/00 ,  C07D471/18 ,  A61K39/00 ,  C07K7/52 ,  C07K16/28 ,  C07D209/14 ,  C07D403/12 ,  C07D417/14

公开(公告)号：EP3609892A1

公开(公告)日：2020-02-19

申请号：EP18717573.2

申请日：2018-04-10

申请人： Bracco Imaging SpA

发明人： LATTUADA, Luciano ,  BUONSANTI, Federica ,  CRIVELLIN, Federico ,  FERRETTI, Fulvio ,  MAISANO, Federico ,  ORIO, Laura ,  PIZZUTO, Lorena

IPC分类号： C07D471/18 ,  C07K7/64 ,  C09B23/08 ,  A61K49/00