公开(公告)号：EP1506178A2

公开(公告)日：2005-02-16

申请号：EP03728951.9

申请日：2003-05-15

申请人： Bristol-Myers Squibb Company

发明人： SUN, Chongqing ,  HAMANN, Lawrence ,  AUGERI, David ,  BI, Yingzhi ,  ROBL, Jeffrey ,  HUANG, Yan-Ting ,  WANG, Tammy ,  SIMPKINS, Ligaya ,  HOLUBEC, Alexandra

IPC分类号： C07D235/00 ,  A61K31/4164

CPC分类号： C07D487/04

摘要： The invention provides for a pharmaceutical composition capable of modulating the androgen receptor comprising a compound of formula (1) wherein the substitutents are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia. Also provided are pharmaceutical compositions containing such compounds and processes for preparing some of the compounds of the invention.