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1.发明公开Extracellular matrix receptor ligands that modulate leukocyte function 失效Rezeptorliganden von der extrazellularen Matrix，die die Leukozytenfunktion modulieren。
公开(公告)号：EP0595659A2
公开(公告)日：1994-05-04
申请号：EP93308688.6
申请日：1993-10-29
CPC分类号： C07K19/00 , A61K38/00 , C07K14/70578 , C07K14/71 , C07K14/715 , C07K2319/02 , C07K2319/30 , C07K2319/32
摘要： Soluble fusion molecule containing the extracellular binding region of leukocyte receptors are described which are capable of binding to extracellular matrix associated proteins. The described lymphocyte to ligand proteins include soluble fusion molecules of 4-1BB, CD27, CD30, FAS, TNF receptor and CD40. A method of modulating leukocyte function is described in which a soluble lymphocyte between leukocyte receptors and the extracellular matrix associated protein of the target tissue.
摘要翻译： 描述了含有白细胞受体的细胞外结合区域的可溶性融合分子，其能够结合细胞外基质相关蛋白质。 所描述的淋巴细胞与配体蛋白包括4-1BB，CD27，CD30，FAS，TNF受体和CD40的可溶性融合分子。 描述了调节白细胞功能的方法，其中白细胞受体与靶组织的细胞外基质相关蛋白之间的可溶性淋巴细胞。
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2.发明公开
公开(公告)号：EP0595659A3
公开(公告)日：1995-01-11
申请号：EP93308688.6
申请日：1993-10-29
CPC分类号： C07K19/00 , A61K38/00 , C07K14/70578 , C07K14/71 , C07K14/715 , C07K2319/02 , C07K2319/30 , C07K2319/32
摘要： Soluble fusion molecule containing the extracellular binding region of leukocyte receptors are described which are capable of binding to extracellular matrix associated proteins. The described lymphocyte to ligand proteins include soluble fusion molecules of 4-1BB, CD27, CD30, FAS, TNF receptor and CD40. A method of modulating leukocyte function is described in which a soluble lymphocyte between leukocyte receptors and the extracellular matrix associated protein of the target tissue.
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