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1.发明公开
公开(公告)号：EP2486030A1
公开(公告)日：2012-08-15
申请号：EP10765715.7
申请日：2010-10-06
发明人： BI, Yingzhi , DZIERBA, Carolyn, Diane , BRONSON, Joanne, J. , CARSON, Kenneth , CIANCHETTA, Giovanni , DONG, Li , FINK, Cynthia , GREEN, Michael , KIMBALL, David , MACOR, John, E. , KWON, Soojin , WANG, Jiancheng , ZHANG, Yulian , ZIPP, Greg
IPC分类号： C07D333/24 , A61K31/381 , C07C233/06 , A61P3/00 , A61P25/00
CPC分类号： C07D333/24 , C07C233/60 , C07C2601/02
摘要： The present disclosure is generally directed to compounds which can modulate G-protein coupled receptor 88, compositions comprising such compounds, and methods for modulating G-protein coupled receptor 88.
摘要翻译： 本公开一般涉及可以调节G蛋白偶联受体88的化合物，包含这些化合物的组合物，以及调节G蛋白偶联受体88的方法。
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公开(公告)号：EP2486030B1
公开(公告)日：2013-07-24
申请号：EP10765715.7
申请日：2010-10-06
发明人： BI, Yingzhi , DZIERBA, Carolyn, Diane , BRONSON, Joanne, J. , CARSON, Kenneth , CIANCHETTA, Giovanni , DONG, Li , FINK, Cynthia , GREEN, Michael , KIMBALL, David , MACOR, John, E. , KWON, Soojin , WANG, Jiancheng , ZHANG, Yulian , ZIPP, Greg
IPC分类号： C07D333/24 , A61K31/381 , C07C233/06 , A61P3/00 , A61P25/00
CPC分类号： C07D333/24 , C07C233/60 , C07C2601/02
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公开(公告)号：EP1893212A2
公开(公告)日：2008-03-05
申请号：EP06752541.0
申请日：2006-05-12
IPC分类号： A61K31/506 , A61K31/496 , A61K31/551 , C07D239/42 , C07D401/12 , C07D401/04 , C07D277/42 , C07D403/04 , C07D487/04 , C07D451/02 , C07D487/08 , A61P25/28
CPC分类号： C07D239/42 , C07D277/42 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D417/04 , C07D451/02 , C07D471/08 , C07D487/04
摘要： This invention relates to multicyclic compounds, pharmaceutical compositions comprising them, and methods of their use in, for example, the treatment of cognitive disorders.
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公开(公告)号：EP1893212B1
公开(公告)日：2013-10-16
申请号：EP06752541.0
申请日：2006-05-12
IPC分类号： A61K31/506 , A61K31/496 , A61K31/551 , C07D239/42 , C07D401/12 , C07D401/04 , C07D277/42 , C07D403/04 , C07D487/04 , C07D451/02 , C07D487/08 , A61P25/28
CPC分类号： C07D239/42 , C07D277/42 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D417/04 , C07D451/02 , C07D471/08 , C07D487/04
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公开(公告)号：EP2089018A2
公开(公告)日：2009-08-19
申请号：EP07871365.8
申请日：2007-11-05
发明人： BARBOSA, Joseph , DONG, Li , FINK, Cynthia Anne , LANTHORN, Thomas Herbert , WANG, Jian Cheng , ZIPP, G. Gregory
IPC分类号： A61K31/397 , A61K31/4025 , A61K31/407 , A61K31/426 , A61K31/435 , A61K31/437 , A61K31/439 , A61K31/4409 , A61K31/496 , A61K31/506 , A61K31/519 , A61K31/551 , A61P25/16 , A61P25/18 , A61P25/28 , A61P43/00
CPC分类号： A61K31/397 , A61K31/4025 , A61K31/407 , A61K31/426 , A61K31/435 , A61K31/437 , A61K31/439 , A61K31/4409 , A61K31/496 , A61K31/506 , A61K31/519 , A61K31/551
摘要： This invention relates to methods for treating, managing and preventing cognitive impairment associated with various diseases and disorders, age-associated memory impairment, and dementia.
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