公开(公告)号：EP2266989B1

公开(公告)日：2015-09-02

申请号：EP09754921.6

申请日：2009-03-31

申请人： C&c Research Laboratories

发明人： AHN, Sung Oh ,  PARK, Chan Hee ,  IM, Jun Hwan ,  LEE, Soon Ok ,  LEE, Kyoung June ,  CHO, Seong Wook ,  KO, Kwang Seok ,  HAN, Sun Young ,  LEE, Won Il

IPC分类号： C07D498/04 ,  A61K31/4375 ,  A61P3/00 ,  A61P9/12

CPC分类号： C07D498/04

公开(公告)号：EP2760865B1

公开(公告)日：2018-07-11

申请号：EP12834688.9

申请日：2012-09-28

申请人： C&C Research Laboratories

发明人： HO, Pil Su ,  YOON, Dong Oh ,  HAN, Sun Young ,  LEE, Won Il ,  KIM, Jung Sook ,  PARK, Woul Seong ,  AHN, Sung Oh ,  KIM, Hye Jung

IPC分类号： C07D471/14 ,  A61K31/4985 ,  A61P29/00 ,  A61P37/08 ,  A61P35/00

CPC分类号： C07D471/14 ,  C07D487/14 ,  C07D498/14 ,  C07D519/00

摘要： The present invention relates to novel heterocyclic compounds useful in preparing drugs for treatment of diseases associated with various functions of the histamine 4 receptor. Especially, the said drugs are useful for treatment of inflammatory diseases, allergy, pain, nasal polyps, rhinitis, chronic sinusitis, nasal congestion, nasal itch, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis, eczema, pruritus, itchy skin, urticaria, idiopathic chronic urticaria, scleroderma, conjunctivitis, keratoconjunctivitis, ocular inflammation, dry eye, cardiac dysfunction, arrhythmia, atherosclerosis, multiple sclerosis, inflammatory bowel disease (including colitis, Crohn's disease, ulcerative colitis), inflammatory pain, neuropathic pain, osteoarthritic pain, autoimmune thyroid disease, immune-mediated (also known as type I) diabetes, lupus, post-operative adhesions, vestibular disorders and cancer.

公开(公告)号：EP3461825A1

公开(公告)日：2019-04-03

申请号：EP18180710.8

申请日：2012-09-28

申请人： C&C Research Laboratories

发明人： HO, Pil Su ,  YOON, Dong Oh ,  HAN, Sun Young ,  LEE, Won Il ,  KIM, Jung Sook ,  PARK, Woul Seong ,  AHN, Sung Oh ,  KIM, Hye Jung

IPC分类号： C07D471/14 ,  A61K31/4985 ,  A61P29/00 ,  A61P37/08 ,  A61P35/00 ,  C07D487/14 ,  C07D498/14 ,  C07D519/00

摘要： The present invention relates to novel heterocyclic compounds useful in preparing drugs for treatment of diseases associated with various functions of the histamine 4 receptor. Especially, the said drugs are useful for treatment of inflammatory diseases, allergy, pain, nasal polyps, rhinitis, chronic sinusitis, nasal congestion, nasal itch, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis, eczema, pruritus, itchy skin, urticaria, idiopathic chronic urticaria, scleroderma, conjunctivitis, keratoconjunctivitis, ocular inflammation, dry eye, cardiac dysfunction, arrhythmia, atherosclerosis, multiple sclerosis, inflammatory bowel disease (including colitis, Crohn's disease, ulcerative colitis), inflammatory pain, neuropathic pain, osteoarthritic pain, autoimmune thyroid disease, immune-mediated (also known as type I) diabetes, lupus, post-operative adhesions, vestibular disorders and cancer.

公开(公告)号：EP2760865A2

公开(公告)日：2014-08-06

申请号：EP12834688.9

申请日：2012-09-28

申请人： C&C Research Laboratories

发明人： HO, Pil Su ,  YOON, Dong Oh ,  HAN, Sun Young ,  LEE, Won Il ,  KIM, Jung Sook ,  PARK, Woul Seong ,  AHN, Sung Oh ,  KIM, Hye Jung

IPC分类号： C07D471/14 ,  A61K31/4985 ,  A61P29/00 ,  A61P37/08 ,  A61P35/00

CPC分类号： C07D471/14 ,  C07D487/14 ,  C07D498/14 ,  C07D519/00

摘要： The present invention relates to novel heterocyclic compounds useful in preparing drugs for treatment of diseases associated with various functions of the histamine 4 receptor. Especially, the said drugs are useful for treatment of inflammatory diseases, allergy, pain, nasal polyps, rhinitis, chronic sinusitis, nasal congestion, nasal itch, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis, eczema, pruritus, itchy skin, urticaria, idiopathic chronic urticaria, scleroderma, conjunctivitis, keratoconjunctivitis, ocular inflammation, dry eye, cardiac dysfunction, arrhythmia, atherosclerosis, multiple sclerosis, inflammatory bowel disease (including colitis, Crohn's disease, ulcerative colitis), inflammatory pain, neuropathic pain, osteoarthritic pain, autoimmune thyroid disease, immune-mediated (also known as type I) diabetes, lupus, post-operative adhesions, vestibular disorders and cancer.

公开(公告)号：EP2266989A2

公开(公告)日：2010-12-29

申请号：EP09754921.6

申请日：2009-03-31

申请人： C&c Research Laboratories

发明人： AHN, Sung Oh ,  PARK, Chan Hee ,  IM, Jun Hwan ,  LEE, Soon Ok ,  LEE, Kyoung June ,  CHO, Seong Wook ,  KO, Kwang Seok ,  HAN, Sun Young ,  LEE, Won Il

IPC分类号： C07D498/04

CPC分类号： C07D498/04

摘要： The present invention relates to heterocyclic derivatives, and more particularly, to novel heterocyclic derivatives useful for the preparation of medicaments for treating diseases related to uric acid.

摘要翻译： 本发明涉及杂环衍生物，更具体地说，涉及可用于制备用于治疗与尿酸相关疾病的药物的新型杂环衍生物。