公开(公告)号：EP1633309A2

公开(公告)日：2006-03-15

申请号：EP04776131.7

申请日：2004-05-27

申请人： CENTOCOR, INC.

发明人： ANDERSON, M., Glenn ,  TAWADROS, Richard ,  NGO, Cam ,  NAKADA, Marian

IPC分类号： A61K6/00

CPC分类号： C07K16/36 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/73

摘要： A method of using tissue factor antagonists to treat proliferative diseases characterized by neovascularization such as cancer, rheumatoid arthritis, psoriasis, or proliferative retinopathy. or macular degeneration. Tissue factor antagonists capable of rapid prevention of blood clotting via the extrinsic pathway are also capable of inhibiting tumor growth in mammals.