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公开(公告)号：EP1029549A1
公开(公告)日：2000-08-23
申请号：EP99942707.3
申请日：1999-09-03
发明人： AGUILAR RUBIDO, Julio César , MUZIO GONZALEZ, Verena Lucila , GUILLEN NIETO, Gerardo Enrique , PENTON ARIAS, Eduardo , LEAL ANGULO, Maria de Jesús , PICHARDO DIAZ, Dagmara Calle 222 No. 2716 , IGLESIAS PEREZ, Enrique Edificio 25 Apto. 103 , HERRERA BUCH, Antonieta , SANDEZ OQUENDO, Bélquis , MUSACCHIO LASA, Alexis , QUINTANA VAZQUEZ, Diógenes , CROMBET MENENDEZ, Lissete
CPC分类号： A61K39/21 , A61K39/0011 , A61K39/12 , A61K39/39 , A61K2039/53 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55583 , C12N2740/16034
摘要： The present invention is related to the medical field, and in particular to the use of new formulations of adjuvants with vaccine antigens. The technical object of the invention is the development of formulations which are capable of potentiating the immune response of the organism to vaccines of nucleic acids. In order to attain this objective, a formulation has been developed which contains as fundamental components the vaccine nucleic acid and acemannan in adequate proportions, in addition to stabilizing and preservative agents. The formulations of the invention are applicable to the pharmaceutical industry as vaccine formulations both for human and animal use.
摘要翻译： 本发明涉及医疗领域，特别涉及使用具有疫苗抗原的佐剂的新制剂。 本发明的技术目的是开发能够增强生物体对核酸疫苗的免疫应答的制剂。 为了达到这个目标，除了稳定剂和防腐剂之外，已经开发出一种配方，其中含有足够比例的疫苗核酸和acemannan作为基本组分。 本发明的制剂适用于作为用于人类和动物使用的疫苗制剂的制药工业。
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公开(公告)号：EP1029549B1
公开(公告)日：2005-02-23
申请号：EP99942707.3
申请日：1999-09-03
发明人： AGUILAR RUBIDO, Julio César , MUZIO GONZALEZ, Verena Lucila , GUILLEN NIETO, Gerardo Enrique , PENTON ARIAS, Eduardo , LEAL ANGULO, Maria de Jesus , PICHARDO DIAZ, Dagmara Calle 222 No. 2716 , IGLESIAS PEREZ, Enrique Edificio 25 Apto. 103 , HERRERA BUCH, Antonieta , SANDEZ OQUENDO, Bélquis , MUSACCHIO LASA, Alexis , QUINTANA VAZQUEZ, Diógenes , CROMBET MENENDEZ, Lissete
CPC分类号： A61K39/21 , A61K39/0011 , A61K39/12 , A61K39/39 , A61K2039/53 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55583 , C12N2740/16034
摘要： The present invention is related to the medical field, and in particular to the use of new formulations of adjuvants with vaccine antigens. The technical object of the invention is the development of formulations which are capable of potentiating the immune response of the organism to vaccines of nucleic acids. In order to attain this objective, a formulation has been developed which contains as fundamental components the vaccine nucleic acid and acemannan in adequate proportions, in addition to stabilizing and preservative agents. The formulations of the invention are applicable to the pharmaceutical industry as vaccine formulations both for human and animal use.
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