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公开(公告)号：EP2842939A4
公开(公告)日：2015-11-11
申请号：EP13782636
申请日：2013-04-24
发明人： MURATA TAKESHI , NIIZUMA SATOSHI , HARA SOUSUKE , KAWADA HATSUO , HADA KIHITO , SHIMADA HIDEAKI , TANAKA HIROSHI , NAKANISHI YOSHITO
IPC分类号： C07C317/32 , A61K31/166 , A61K31/40 , A61K31/445 , A61K31/495 , A61K31/496 , A61P19/04 , A61P29/00 , A61P35/00 , A61P35/02 , A61P43/00 , C07C211/56 , C07C317/34 , C07C323/42 , C07C323/46 , C07D205/04 , C07D207/09 , C07D207/12 , C07D207/14 , C07D211/26
CPC分类号： C07C321/28 , C07C317/14 , C07C317/34 , C07C317/40 , C07C323/42 , C07C323/48 , C07C2601/02 , C07D205/04 , C07D207/09 , C07D207/12 , C07D207/14 , C07D211/26 , C07D211/56 , C07D211/68 , C07D213/62 , C07D213/82 , C07D241/04 , C07D263/34 , C07D295/14 , C07D295/16 , C07D309/14 , C07D401/12 , C07D403/04 , C07D487/08
摘要： The present invention relates to benzamide derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
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公开(公告)号：EP2842946A4
公开(公告)日：2015-09-09
申请号：EP13781062
申请日：2013-04-24
发明人： MURATA TAKESHI , KAWADA HATSUO , NIIZUMA SATOSHI , HARA SOUSUKE , HADA KIHITO , SHIMADA HIDEAKI , TANAKA HIROSHI , MIO TOSHIYUKI
IPC分类号： C07D239/96 , A61K31/517 , A61K31/5377 , A61P19/04 , A61P29/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D401/06 , C07D401/14 , C07D403/06 , C07D405/04 , C07D405/12 , C07D487/04
CPC分类号： C07D239/96 , C07D401/06 , C07D401/14 , C07D403/06 , C07D405/04 , C07D405/12 , C07D487/04
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公开(公告)号：EP2441753A4
公开(公告)日：2014-08-27
申请号：EP10786195
申请日：2010-06-09
发明人： KINOSHITA KAZUTOMO , ASOH KOHSUKE , FURUICHI NORIYUKI , ITO TOSHIYA , KAWADA HATSUO , ISHII NOBUYA , SAKAMOTO HIROSHI , HONG WOOSANG , PARK MINJEONG , ONO YOSHIYUKI , KATO YASUHARU , MORIKAMI KENJI , EMURA TAKASHI , OIKAWA NOBUHIRO
IPC分类号： C07D209/88 , A61K31/343 , A61K31/381 , A61K31/403 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61P25/24 , A61P25/28 , A61P35/00 , A61P35/02 , A61P35/04 , A61P43/00
CPC分类号： C07D209/58 , A61K31/404 , A61K31/4178 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7056 , C07D209/56 , C07D209/88 , C07D307/77 , C07D307/78 , C07D307/92 , C07D333/50 , C07D333/52 , C07D333/76 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/14 , C07D471/04 , C07D471/10 , C07D491/107 , C07F7/0834 , C07H15/26
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公开(公告)号：EP3061749A4
公开(公告)日：2017-05-31
申请号：EP14855498
申请日：2014-10-23
发明人： MURATA TAKESHI , HARA SOUSUKE , NIIZUMA SATOSHI , HADA KIHITO , KAWADA HATSUO , SAKAITANI MASAHIRO , SHIMADA HIDEAKI , NAKANISHI YOSHITO
IPC分类号： C07D217/24 , A61K31/472 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/553 , A61P11/00 , A61P29/00 , A61P35/00 , A61P35/04 , C07D239/91 , C07D239/94 , C07D401/06 , C07D401/12 , C07D403/06
CPC分类号： C07D239/92 , C07D217/24 , C07D239/90 , C07D239/91 , C07D239/94 , C07D401/06 , C07D401/12 , C07D403/06 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/12 , C07D409/12 , C07D413/06 , C07D471/04 , C07D487/04 , C07D491/056
摘要： The present invention relates to quinazolinone and isoquinolinone derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
摘要翻译： 本发明涉及由式（I）表示的喹唑啉酮和异喹啉酮衍生物或其药学上可接受的盐。
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公开(公告)号：EP2050749A4
公开(公告)日：2011-03-30
申请号：EP07792065
申请日：2007-08-07
发明人： SHIMMA NOBUO , EBIIKE HIROSATO , OHWADA JUN , KAWADA HATSUO , MORIKAMI KENJI , NAKAMURA MITSUAKI , YOSHIDA MIYUKI , ISHII NOBUYA , HASEGAWA MASAMI , YAMAMOTO SHUN , KOYAMA KOHEI
IPC分类号： C07D487/04 , A61K31/5377 , A61P35/00
CPC分类号： C07D487/04
摘要： A drug is provided that is useful as a preventive or therapeutic for cancer as a result of having superior PI3K inhibitory effects as well as superior stability in the body and water-solubility. A compound, or pharmaceutically acceptable salt thereof, represented by formula (I): [wherein, X represents a single bond, etc.; Y represents a single bond, etc. (provided that X and Y are not simultaneously single bonds); Z represents a hydrogen atom, etc.; m represents an integer of 1 or 2; and R 1 represents a cyclic substituent].
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