公开(公告)号：EP2968366A4

公开(公告)日：2016-09-07

申请号：EP14765688

申请日：2014-03-17

申请人： CLARUS THERAPEUTICS INC

发明人： DUDLEY ROBERT E ,  CONSTANTINIDES PANAYIOTIS P ,  LONGSTRETH JAMESA

IPC分类号： A61K31/568 ,  A61K9/48 ,  A61K47/30 ,  A61P5/26

CPC分类号： A61K31/568 ,  A61K9/0053 ,  A61K9/4858 ,  A61K47/10 ,  A61K47/14 ,  A61K47/44

摘要： Methods of treating a testosterone deficiency or its symptoms with a pharmaceutical formulation of testosterone esters are provided. The methods are designed toprovide optimum serum testosterone levels over an extended period.

公开(公告)号：EP1871384A4

公开(公告)日：2012-01-25

申请号：EP06758358

申请日：2006-04-14

申请人： CLARUS THERAPEUTICS INC

发明人： DUDLEY ROBERT E ,  CONSTANTINIDES PANAYIOTIS P

IPC分类号： A61K31/56 ,  A61K31/568 ,  A61K47/44 ,  A61P5/26

CPC分类号： A61K31/568 ,  A61K9/0053 ,  A61K9/06 ,  A61K9/1075 ,  A61K9/4858 ,  A61K31/22 ,  A61K31/573 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/26 ,  A61K47/44 ,  C07J1/00 ,  A61K2300/00

摘要： A drug delivery system for oral administration of hydrophobic drugs with enhanced and extended absorption and improved pharmacokinetics is provided. In one embodiment, formulations comprising testosterone and testosterone esters are disclosed. Method of treating a hormone deficiency or effecting male contraception with the formulations are also provided.