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1.发明公开PROTEINE SPECIFIQUE DES CELLULES PANCREATIQUES BETA DES ILOTS DE LANGERHANS ET SES APPLICATIONS. 有权蛋白特异性朗格汉斯群岛及其使用胰腺β细胞，
公开(公告)号：EP1563071A2
公开(公告)日：2005-08-17
申请号：EP03786019.4
申请日：2003-11-18
发明人： SEVE, Michel , FAVIER, Alain
IPC分类号： C12N15/12 , C07K14/705 , C07K16/28 , C12Q1/68 , G01N33/50 , G01N33/53 , A01K67/027 , C12N15/11
CPC分类号： G01N33/6872 , A01K2217/05 , A61K38/00 , C07K14/705 , C07K16/28 , C07K2317/34 , C12Q1/6883 , C12Q2600/158 , G01N2500/04 , G01N2500/10
摘要： The invention relates to protein ZnT-8 which is specifically expressed in the pancreatic beta cells in islets of Langerhans, to a polynucleotide encoding said protein which is involved in the maturation and exocytosis of insulin, and to the applications thereof, for example, for sorting and studying beta cells and for screening medicine acting on diabetes and hyperinsulinism.
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2.发明授权PROTEINE SPECIFIQUE DES CELLULES PANCREATIQUES BETA DES ILOTS DE LANGERHANS ET SES APPLICATIONS. 有权蛋白特异性朗格汉斯群岛及其使用胰腺β细胞，
公开(公告)号：EP1563071B1
公开(公告)日：2008-09-17
申请号：EP03786019.4
申请日：2003-11-18
发明人： SEVE, Michel , FAVIER, Alain
IPC分类号： C12N15/12 , C07K14/705 , C07K16/28 , C12Q1/68 , G01N33/50 , G01N33/53 , A01K67/027 , C12N15/11
CPC分类号： G01N33/6872 , A01K2217/05 , A61K38/00 , C07K14/705 , C07K16/28 , C07K2317/34 , C12Q1/6883 , C12Q2600/158 , G01N2500/04 , G01N2500/10
摘要： The invention relates to protein ZnT-8 which is specifically expressed in the pancreatic beta cells in islets of Langerhans, to a polynucleotide encoding said protein which is involved in the maturation and exocytosis of insulin, and to the applications thereof, for example, for sorting and studying beta cells and for screening medicine acting on diabetes and hyperinsulinism.
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