MICROORGANISMES AYANT UNE ACTION MODULATRICE DE LA GLYCOSYLATION DE SURFACE DES CELLULES INTESTINALES
    1.
    发明公开
    MICROORGANISMES AYANT UNE ACTION MODULATRICE DE LA GLYCOSYLATION DE SURFACE DES CELLULES INTESTINALES 有权
    微生物类肠细胞的演技OBERFLÄCHENGLYKOLYSIERUNG

    公开(公告)号:EP1297176A1

    公开(公告)日:2003-04-02

    申请号:EP01951775.4

    申请日:2001-07-04

    IPC分类号: C12Q1/02 C12R1/225

    CPC分类号: C12Q1/02

    摘要: The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteria, which consists in measuring the average fluorescence intensity variation of HT29-MTX cells incubated in the presence of a lectin coupled with a fluorochrome after being in contact with the supernatant of the strain concerned. Said lactic acid bacteria strains can be used, optionally in the form of their active fraction, for preparing food compositions or medicines or food supplements, modulating glycosylation of glycoproteins of intestinal epithelial cells.

    MICROORGANISMES AYANT UNE ACTION MODULATRICE DE LA GLYCOSYLATION DE SURFACE DES CELLULES INTESTINALES
    2.
    发明授权
    MICROORGANISMES AYANT UNE ACTION MODULATRICE DE LA GLYCOSYLATION DE SURFACE DES CELLULES INTESTINALES 有权
    微生物类肠细胞的演技OBERFLÄCHENGLYKOLYSIERUNG

    公开(公告)号:EP1297176B1

    公开(公告)日:2006-07-19

    申请号:EP01951775.4

    申请日:2001-07-04

    IPC分类号: C12Q1/02 C12R1/225

    CPC分类号: C12Q1/02

    摘要: The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteria, which consists in measuring the average fluorescence intensity variation of HT29-MTX cells incubated in the presence of a lectin coupled with a fluorochrome after being in contact with the supernatant of the strain concerned. Said lactic acid bacteria strains can be used, optionally in the form of their active fraction, for preparing food compositions or medicines or food supplements, modulating glycosylation of glycoproteins of intestinal epithelial cells.