公开(公告)号：EP0781758A1

公开(公告)日：1997-07-02

申请号：EP96850044.7

申请日：1996-03-08

申请人： CPS CHEMICAL COMPANY, Inc.

发明人： Trapasso, Louis E. ,  Meisel, Philip L. ,  Meisel, Lee B. ,  Chwang, Willy Kao-Ying

IPC分类号： C07C67/03 ,  C07C69/54

CPC分类号： C07C67/03 ,  C07C2601/20 ,  C07C2602/42 ,  C07C69/54

摘要： Methyl or ethyl esters of mono- and polycarboxylic acids are transesterified with alcohols and polyols by reaction in the presence of a catalytically effective amount of an organotin catalyst having the structure:
wherein for each Sn, A is independently selected from alkyl groups containing from 1 to 4 carbon atoms, and X is independently selected from alkyl, chlorine, bromine, hydroxyl, 1-18 carbon atom alkoxy and 1-18 carbon atom acyloxy groups, provided that when X is alkyl, the total number of carbon atoms in A and X for each Sn is no more than 4, and when X is not alkyl, the total number of carbon atoms in A for each Sn is no more than 4;

Y is selected from chlorine, bromine, hydroxyl, 1-18 carbon atom alkoxy and 1-18 carbon atom acyloxy groups, R is selected from hydrogen, 1-18 carbon atom alkyl and 1-18 carbon atom acyl groups, or Y, X and -O-R together form a stannanoic acid group or an anhydride thereof, and N is an integer from 1 to 10;
so that an alcohol or polyol carboxylic acid ester is formed, which is then washed with aqueous alkali having a pH greater than about 13.2, so as to remove essentially all of the organotin catalyst, thereby permitting the recovery of the alcohol or polyol carboxylic acid ester essentially free of the organotin catalyst.

摘要翻译： 在催化有效量的具有以下结构的有机锡催化剂的存在下，单羧酸和多羧酸的甲酯或乙酯与醇和多元醇进行酯交换：其中对于每个Sn，A独立地选自含有 1至4个碳原子，X独立地选自烷基，氯，溴，羟基，1-18个碳原子烷氧基和1-18个碳原子的酰氧基，条件是当X是烷基时，碳原子总数 A和X对于每个Sn不大于4，当X不是烷基时，每个Sn中A的总碳原子数不超过4; Y选自氯，溴，羟基，1-18个碳原子的烷氧基和1-18个碳原子的酰氧基，R选自氢，1-18个碳原子的烷基和1-18个碳原子的酰基，或Y，X 和-OR一起形成苯乙酸基或其酸酐，N为1至10的整数; 使得形成醇或多元醇羧酸酯，然后用pH大于约13.2的碱性水溶液洗涤，以便基本上除去所有有机锡催化剂，从而允许回收醇或多元醇羧酸酯 基本上不含有机锡催化剂。