专利检索 ap:("CYTEL CORPORATION") AND inv:"ELICES, Mariano, J." 第 1 页

1.

发明公开
CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME 失效
标题翻译： CS - 1个模拟肽Zusammensetzunge及其应用方法

公开(公告)号：EP0737204A1

公开(公告)日：1996-10-16

申请号：EP95903199.0

申请日：1994-12-05

申请人： CYTEL CORPORATION

发明人： ARRHENIUS, Thomas, S. , ELICES, Mariano, J. , GAETA, Federico, C., A.

IPC分类号： C07K5 , C07K7 , C07K14 , A61K38

CPC分类号： C07K7/06 , A61K38/00 , C07K5/0205 , C07K5/0207 , C07K5/021 , C07K5/06034 , C07K5/06113 , C07K5/0804 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/0819 , C07K5/0821 , C07K5/1005 , C07K5/1008 , C07K5/101 , C07K5/1013 , C07K5/1016 , C07K5/1019 , C07K14/78

摘要： The present invention contemplates a peptide that inhibits the binding between the VLA-4 receptor expressed on inflammatory leukocytes and the fibronectin CS-1 peptide expressed on endothelial cells that are involved in immunoinflammatory disease states. Pharmaceutical compositions containing a contemplated peptide and processes for treating immunoinflammatory conditions using a binding-inhibitory peptide are also disclosed.

2.

发明公开
CYCLIC CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME 失效
标题翻译：循环CS-1肽MIMMETICA，组成和使用方法他们

公开(公告)号：EP0777681A2

公开(公告)日：1997-06-11

申请号：EP95931586.0

申请日：1995-08-25

申请人： CYTEL CORPORATION

发明人： ARRHENIUS, Thomas, S. , ELICES, Mariano, J. , TEMPCZYK, Anna , ZHENG, Zhong-Li

IPC分类号： C07K5 , C07K14 , A61K38

CPC分类号： C07K5/1024 , A61K38/00 , C07K5/0808 , C07K5/1013 , C07K5/126 , C07K14/78 , Y10S930/26 , Y10S930/27

摘要： The present invention contemplates a cyclic peptide that inhibits the binding between the VLA-4 receptor expressed on inflammatory leukocytes and the fibronectin CS-1 peptide expressed on endothelial cells that are involved in immunoinflammatory disease states. Pharmaceutical compositions containing a contemplated cyclic peptide and processes for treating immunoinflammatory conditions using a binding-inhibitory cyclic peptide are also disclosed.