公开(公告)号：EP4349308A2

公开(公告)日：2024-04-10

申请号：EP24151329.0

申请日：2019-06-11

申请人： California Institute of Technology ,  The University of Southern California

发明人： TAI, Yu-Chong ,  SCIANMARELLO, Nicholas E. ,  COOK, Colin A. ,  HUMAYUN, Mark S.

IPC分类号： A61F9/00

摘要： An eye treatment apparatus is described. The apparatus includes an annular body that has a hollow optical zone in its center. An inner perimeter of the annular body surrounds the optical zone. The inner perimeter has a diameter that corresponds to a diameter of the eye's cornea. An outer perimeter of the annular body has a diameter such that the annular body can extend to underneath the eye lid in an open eye position when the eye treatment apparatus is in operation. In this way, the apparatus can be worn on the eye, where the hollow optical zone substantially corresponds to the cornea and does not interfere with the field of vision. The annular body also includes a storage chamber that stores therapeutic liquid for an eye. An outlet is coupled with the storage chamber such that, in operation, the therapeutic liquid can be dispensed to the eye.

公开(公告)号：EP3346950A1

公开(公告)日：2018-07-18

申请号：EP16845180.5

申请日：2016-09-09

申请人： California Institute of Technology ,  The University of Southern California ,  Doheny Eye Institute

发明人： TAI, Yu-Chong ,  SCIANMARELLO, Nicholas E. ,  MURALI, Karthik ,  HUMAYUN, Mark S. ,  RIBEIRO, Ramiro Magalhaes

IPC分类号： A61F2/14 ,  A61F9/00 ,  A61M5/00 ,  A61M5/142 ,  A61M31/00 ,  A61M35/00

CPC分类号： A61F9/0017 ,  A61M5/14276 ,  A61M37/00 ,  A61M2005/14204 ,  A61M2205/04 ,  A61M2210/0612 ,  A61N1/0543 ,  A61N1/20 ,  A61N1/3787

摘要： An implantable medical device is described. The implantable medical device includes a small molecule generator, a small molecule diffusor, and a cannula that connects the two. The small molecule generator includes an electrolyte reservoir and a set of electrodes. A first portion of the electrolyte reservoir is impermeable to a predetermined class of small molecules. A second portion of the electrolyte reservoir is permeable to the small molecules. The set of electrodes is disposed inside the electrolyte reservoir and is configured to facilitate electrolysis of the small molecules based on an electric power application to the set of electrodes and on presence of electrolyte inside the electrolyte reservoir. At least a portion of the small molecule diffusor is permeable to the small molecules.

公开(公告)号：EP3801466A1

公开(公告)日：2021-04-14

申请号：EP19820418.2

申请日：2019-06-11

申请人： California Institute of Technology ,  THE UNIVERSITY OF SOUTHERN CALIFORNIA

发明人： TAI, Yu-Chong ,  SCIANMARELLO, Nicholas E. ,  COOK, Colin A. ,  HUMAYUN, Mark S.

IPC分类号： A61K9/00

公开(公告)号：EP4349308A3

公开(公告)日：2024-06-19

申请号：EP24151329.0

申请日：2019-06-11

申请人： California Institute of Technology ,  The University of Southern California

发明人： TAI, Yu-Chong ,  SCIANMARELLO, Nicholas E. ,  COOK, Colin A. ,  HUMAYUN, Mark S.

IPC分类号： A61F9/00

CPC分类号： A61F9/0017 ,  A61K9/0051 ,  A61P27/00 ,  G02C7/04

摘要： An eye treatment apparatus is described. The apparatus includes an annular body that has a hollow optical zone in its center. An inner perimeter of the annular body surrounds the optical zone. The inner perimeter has a diameter that corresponds to a diameter of the eye's cornea. An outer perimeter of the annular body has a diameter such that the annular body can extend to underneath the eye lid in an open eye position when the eye treatment apparatus is in operation. In this way, the apparatus can be worn on the eye, where the hollow optical zone substantially corresponds to the cornea and does not interfere with the field of vision. The annular body also includes a storage chamber that stores therapeutic liquid for an eye. An outlet is coupled with the storage chamber such that, in operation, the therapeutic liquid can be dispensed to the eye.