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1.发明公开Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy 审中-公开肺疾病及其试剂盒的鉴定，评估，预防和治疗方法，包括基于性别的疾病鉴定，评估，预防和治疗
公开(公告)号：EP2857522A2
公开(公告)日：2015-04-08
申请号：EP14182060.5
申请日：2010-03-12
IPC分类号： C12Q1/68 , C12N15/12 , G01N33/574 , G01N33/68
CPC分类号： G01N33/57423 , G01N33/6893 , G01N2800/12
摘要： The invention provides biomarkers and combinations of biomarkers useful in diagnosing lung diseases such as non-small cell lung cancer or reactive airway disease. The invention also provides methods of differentiating lung disease, methods of monitoring therapy, and methods of predicting a subject's response to therapeutic intervention based on the extent of expression of the biomarkers and combinations of biomarkers. Kits comprising agents for detecting the biomarkers and combination of biomarkers are also provided.
摘要翻译： 本发明提供了用于诊断肺病例如非小细胞肺癌或反应性气道疾病的生物标志物和生物标志物的组合。 本发明还提供了基于生物标志物和生物标志物组合的表达程度，区分肺部疾病的方法，监测治疗方法以及预测受试者对治疗性干预的反应的方法。 还提供了包含用于检测生物标志物和生物标志物组合的试剂盒。
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2.发明公开Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy 审中-公开一种用于肺部疾病的鉴定，评估，预防和治疗以及为此与性别特异性疾病识别，评估，预防和治疗的试剂盒过程
公开(公告)号：EP2857522A3
公开(公告)日：2015-10-14
申请号：EP14182060.5
申请日：2010-03-12
IPC分类号： C12Q1/68 , C12N15/12 , G01N33/574 , G01N33/68
CPC分类号： G01N33/57423 , G01N33/6893 , G01N2800/12
摘要： The invention provides biomarkers and combinations of biomarkers useful in diagnosing lung diseases such as non-small cell lung cancer or reactive airway disease. The invention also provides methods of differentiating lung disease, methods of monitoring therapy, and methods of predicting a subject's response to therapeutic intervention based on the extent of expression of the biomarkers and combinations of biomarkers. Kits comprising agents for detecting the biomarkers and combination of biomarkers are also provided.
摘要翻译： 本发明提供生物标记物和诊断肺病有用的生物标记物的组合：如非小细胞肺癌或反应性气道疾病。 因此，本发明提供了一种预测基于生物标志物的生物标志物和组合的表达的程度，治疗性干预的受试者的响应的区分肺疾病的方法，监控治疗的方法，与方法。 因此，提供包括用于检测所述生物标志物和生物标记物的组合试剂的试剂盒。
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