公开(公告)号：EP3013257A1

公开(公告)日：2016-05-04

申请号：EP14818179.5

申请日：2014-06-27

申请人： Cardiovascular Systems, Inc.

发明人： SCHOENLE, Victor Leo ,  MCBROOM, Jeffrey A.

IPC分类号： A61B17/22

CPC分类号： A61B17/320758 ,  A61B17/320725 ,  A61B17/32075 ,  A61B2017/320004 ,  A61B2017/320032 ,  A61B2017/320766 ,  A61B2017/320775

摘要： An atherectomy device may include a handle having a rotational drive mechanism therein, a drive shaft operably coupled to the drive mechanism and having an abrasive element arranged at a distal end thereof, the drive shaft comprising a first portion and a second portion, wherein the first portion comprises a spin-to-close profile and the second portion comprises a spin-to-open profile.

摘要翻译： 动脉粥样斑块切除装置可以包括在其中具有旋转驱动机构的手柄，可操作地联接到驱动机构并具有布置在其远端处的研磨元件的驱动轴，驱动轴包括第一部分和第二部分，其中第一部分 部分包括自旋关闭轮廓，并且第二部分包括旋转至打开轮廓。

公开(公告)号：EP3313499A1

公开(公告)日：2018-05-02

申请号：EP16815370.8

申请日：2016-06-24

申请人： Cardiovascular Systems, Inc.

发明人： SCHOENLE, Victor L. ,  CAMBRONNE, Matthew D. ,  PUSEY, Brittany N. ,  MCBROOM, Jeffrey A.

IPC分类号： A61M25/10 ,  A61M37/00 ,  A61N7/00 ,  A61B17/3207 ,  A61M5/142 ,  A61M25/09

摘要： The present disclosure generally relates to methods, devices and systems relating to applying drugs or therapeutic agents to biological conduits, e.g., vascular lumens. More specifically, the present invention comprises enhancing the uptake of drugs or therapeutic agents encapsulated in microbubbles in combination with ultrasound energy as well as applying drugs or therapeutic agents in a cyclic manner using a pulse generator that may be matched in frequency with a patient's blood pulsing.

公开(公告)号：EP3313499B1

公开(公告)日：2020-03-18

申请号：EP16815370.8

申请日：2016-06-24

申请人： Cardiovascular Systems, Inc.

发明人： SCHOENLE, Victor L. ,  CAMBRONNE, Matthew D. ,  PUSEY, Brittany N. ,  MCBROOM, Jeffrey A.

IPC分类号： A61K41/00 ,  A61M25/10 ,  A61M37/00 ,  A61B17/3207

公开(公告)号：EP2536351A1

公开(公告)日：2012-12-26

申请号：EP11745289.6

申请日：2011-02-18

申请人： Cardiovascular Systems, Inc.

发明人： GENNRICH, David J. ,  MCBROOM, Jeffrey A. ,  TIBESAR JENSEN, Kristina ,  RIVERS, Jody Lee

IPC分类号： A61F2/06

CPC分类号： A61B17/22 ,  A61B17/32037 ,  A61B2017/00004 ,  A61B2017/22002 ,  A61B2017/22051 ,  A61B2017/22061 ,  A61B2017/22084 ,  A61F2/07 ,  A61F2/90 ,  A61F2002/077 ,  A61F2220/0016 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0003 ,  A61F2250/003 ,  A61F2250/0068 ,  A61L2300/604 ,  A61M37/0069

摘要： The invention provides a system, device and method for localized application of therapeutic substances within a biological conduit. In various embodiments, a dissolvable bag or bolus of at least one therapeutic agent is introduced and pressed and/or sealed against the wall of conduit. In other embodiments, dissolvable barbs formed from at least one therapeutic agent are ejected from a catheter by fluid pressure, embedding in the wall of conduit.