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1.发明公开
公开(公告)号：EP4296285A3
公开(公告)日：2024-02-28
申请号：EP23192639.5
申请日：2019-04-26
发明人： BILSBOROUGH, Janine , MCGOVERN, Dermot P. , TARGAN, Stephan , POTDAR, Alka , WATKINS, Jeffry, D. , DICKERSON, Cindy, T.
IPC分类号： C12Q1/6883 , C07K16/24 , A61K39/395
摘要： Described herein are methods and systems for identifying subjects suitable for treatment with an inhibitor of CD30L activity or expression, such as an anti-CD30L antibody. Methods and systems disclosed herein identify subjects suitable for treatment based on a presence of a genotype that is indicative of a disease or condition in the subject for which an inhibitor of CD30L is a suitable treatment. Exemplary conditions include both Crohn's disease and primary sclerosing cholangitis. Compositions used to detect the genotypes described herein, and methods of using them are also provided.
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2.发明公开
公开(公告)号：EP4296285A2
公开(公告)日：2023-12-27
申请号：EP23192639.5
申请日：2019-04-26
发明人： BILSBOROUGH, Janine , MCGOVERN, Dermot P. , TARGAN, Stephan , POTDAR, Alka , WATKINS, Jeffry, D. , DICKERSON, Cindy, T.
IPC分类号： C07K16/28
摘要： Described herein are methods and systems for identifying subjects suitable for treatment with an inhibitor of CD30L activity or expression, such as an anti-CD30L antibody. Methods and systems disclosed herein identify subjects suitable for treatment based on a presence of a genotype that is indicative of a disease or condition in the subject for which an inhibitor of CD30L is a suitable treatment. Exemplary conditions include both Crohn's disease and primary sclerosing cholangitis. Compositions used to detect the genotypes described herein, and methods of using them are also provided.
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3.发明公开
公开(公告)号：EP3774897A1
公开(公告)日：2021-02-17
申请号：EP19796203.8
申请日：2019-04-26
发明人： BILSBOROUGH, Janine , MCGOVERN, Dermot P. , TARGAN, Stephan , POTDAR, Alka , WATKINS, Jeffry, D. , DICKERSON, Cindy, T.
IPC分类号： C07K16/24 , A61K39/395 , C12Q1/68
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