公开(公告)号：EP1448165B1

公开(公告)日：2007-09-19

申请号：EP02774211.3

申请日：2002-11-13

申请人： Celator Pharmaceuticals, Inc.

发明人： WEBB, Murray ,  TARDI, Paul

IPC分类号： A61K9/00

CPC分类号： A61K9/1271 ,  A61K9/1272 ,  A61K9/1278

摘要： Liposomal compositions which have enhanced retention properties for biological agents are characterized by an intrasomal osmolarity of 500 mOSM/kg or less and by containing substantially no cholesterol. The liposomes comprise vesicle forming lipids along with aggregation preventing components, and typically have transition temperatures of 38 °C or higher.

公开(公告)号：EP1443900B1

公开(公告)日：2012-05-23

申请号：EP02774210.5

申请日：2002-11-13

申请人： Celator Pharmaceuticals, Inc.

发明人： WEBB, Murray ,  TARDI, Paul ,  MAYER, Lawrence, D. ,  ICKENSTEIN, Ludger, M.

IPC分类号： A61K9/00

CPC分类号： A61K9/1271 ,  A61K9/127 ,  A61K9/1278

摘要： Liposomes that contain at least 10 mol % of a negatively charged lipid coupled to an non-zwitterionic moiety are stable in the blood. Liposomes containing at least 1 mol % of such lipids may be frozen safely.

公开(公告)号：EP1817005A1

公开(公告)日：2007-08-15

申请号：EP05849544.1

申请日：2005-11-18

申请人： Celator Pharmaceuticals, Inc.

发明人： TARDI, Paul ,  WEBB, Murray ,  JOHNSTONE, Sharon ,  HARVIE, Pierrot ,  MAYER, Lawrence

IPC分类号： A61K9/127

CPC分类号： A61K9/127 ,  A61K9/1278

摘要： This invention relates to encapsulation of drugs and other agents into preformed delivery vehicles.

公开(公告)号：EP1617828A2

公开(公告)日：2006-01-25

申请号：EP04725252.3

申请日：2004-04-02

申请人： Celator Pharmaceuticals, Inc.

发明人： TARDI, Paul ,  HARASYM, Troy ,  WEBB, Murray ,  SHEW, Clifford

IPC分类号： A61K31/00

CPC分类号： A61K9/127 ,  A61K9/1075 ,  A61K9/51 ,  A61K45/06

摘要： Delivery vehicle compositions having stably associated therewith at least one therapeutic agent and at least one drug resistance modulator are useful in achieving a biologic effect to a drug resistance target.

公开(公告)号：EP1432402B1

公开(公告)日：2006-11-22

申请号：EP02766997.7

申请日：2002-10-03

申请人： Celator Pharmaceuticals, Inc.

发明人： TARDI, Paul ,  HARASYM, Troy ,  WEBB, Murray ,  SHEW, Clifford ,  MAYER, Lawrence ,  BALLY, Marcel ,  JANOFF, Andrew

IPC分类号： A61K9/00

CPC分类号： A61K45/06 ,  A61K9/127 ,  A61K9/1271 ,  A61K9/1272 ,  A61K31/00 ,  A61K31/337 ,  A61K31/4745 ,  A61K31/704 ,  A61K31/7048 ,  A61K31/7072 ,  A61K31/7076 ,  A61K33/24 ,  A61K2300/00

摘要： Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.

公开(公告)号：EP1432403B1

公开(公告)日：2010-07-28

申请号：EP02766998.5

申请日：2002-10-03

申请人： Celator Pharmaceuticals, Inc.

发明人： TARDI, Paul ,  JOHNSTONE, Sharon ,  WEBB, Murray ,  BALLY, Marcel ,  ABRAHAM, Sheela

IPC分类号： A61K9/127

CPC分类号： A61K31/7072 ,  A61K9/127 ,  A61K9/1271 ,  A61K9/1272 ,  A61K31/00 ,  A61K31/4745 ,  A61K31/704 ,  A61K31/7048 ,  A61K31/7076 ,  A61K33/24 ,  A61K45/06 ,  A61K2300/00