公开(公告)号：EP1786443B1

公开(公告)日：2018-06-06

申请号：EP05773414.7

申请日：2005-07-19

申请人： Celator Pharmaceuticals, Inc. ,  The Trustees of Princeton University

发明人： MAYER, Lawrence, D. ,  PRUD'HOMME, Robert, K. ,  ALLEN, Christine, J. ,  SAAD, Walid, S.

IPC分类号： A61K31/74 ,  A61K31/77 ,  A61K8/85 ,  A61K9/51 ,  A61K45/06 ,  A61K47/55 ,  A61K47/58 ,  A61K47/59 ,  A61K47/60 ,  A61K47/69 ,  A61Q17/04 ,  B82Y5/00

CPC分类号： A61K47/6931 ,  A61K8/85 ,  A61K9/5153 ,  A61K45/06 ,  A61K47/22 ,  A61K47/54 ,  A61K47/543 ,  A61K47/545 ,  A61K47/55 ,  A61K47/551 ,  A61K47/552 ,  A61K47/58 ,  A61K47/59 ,  A61K47/593 ,  A61K47/60 ,  A61K47/6935 ,  A61K2800/57 ,  A61Q17/04 ,  B82Y5/00

摘要： Particulate constructs stabilized by amphiphilic copolymers and comprising at least one active coupled to a hydrophobic moiety provide sustained release of the active in both in vitro and in vivo environments.

公开(公告)号：EP1443900B1

公开(公告)日：2012-05-23

申请号：EP02774210.5

申请日：2002-11-13

申请人： Celator Pharmaceuticals, Inc.

发明人： WEBB, Murray ,  TARDI, Paul ,  MAYER, Lawrence, D. ,  ICKENSTEIN, Ludger, M.

IPC分类号： A61K9/00

CPC分类号： A61K9/1271 ,  A61K9/127 ,  A61K9/1278

摘要： Liposomes that contain at least 10 mol % of a negatively charged lipid coupled to an non-zwitterionic moiety are stable in the blood. Liposomes containing at least 1 mol % of such lipids may be frozen safely.

公开(公告)号：EP1786443A2

公开(公告)日：2007-05-23

申请号：EP05773414.7

申请日：2005-07-19

申请人： Celator Pharmaceuticals, Inc. ,  The Trustees of Princeton University

发明人： MAYER, Lawrence, D. ,  PRUD'HOMME, Robert, K. ,  ALLEN, Christine, J. ,  SAAD, Walid, S.

IPC分类号： A61K31/74 ,  A61K31/77

CPC分类号： A61K47/482 ,  A61K8/85 ,  A61K9/5153 ,  A61K45/06 ,  A61K47/22 ,  A61K47/48107 ,  A61K47/48192 ,  A61K47/551 ,  A61K47/552 ,  A61K47/58 ,  A61K47/59 ,  A61K47/593 ,  A61K47/60 ,  A61K47/6935 ,  A61K2800/57 ,  A61Q17/04 ,  B82Y5/00

摘要： Particulate constructs stabilized by amphiphilic copolymers and comprising at least one active coupled to a hydrophobic moiety provide sustained release of the active in both in vitro and in vivo environments.