公开(公告)号：EP3418717A1

公开(公告)日：2018-12-26

申请号：EP17177624.8

申请日：2017-06-23

申请人： Cellix Limited

发明人： Kashanin, Dmitry ,  Shvets, Igor ,  Mc Auley, Robert

IPC分类号： G01N15/10 ,  C12N5/071 ,  B01L3/00 ,  G01N15/14

CPC分类号： G01N15/10 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/0864 ,  B01L2400/0415 ,  C12N5/0612 ,  G01N15/1056 ,  G01N15/1459 ,  G01N15/1484 ,  G01N2015/1006 ,  G01N2015/1081

摘要： A microfluidic apparatus for separation of particulates in a fluidAn apparatus for separation of particulates in a fluid (3A) into subsets of particulates comprises a microfluidic chip (1) comprising: a microfluidic channel having a fluid inlet for receipt of a stream of particulate containing fluid (3A), a detection zone disposed in the microfluidic channel and comprising a sensor configured to detect changes in the microfluidic channel corresponding to particulates passing the sensor, and a separation zone distal of the detection zone in which the microfluidic channel divides into at least two secondary microfluidic channels (4). The separation zone comprises two or more separation electrodes (16A, 16B) including at least one separation electrode (16A, 16B, 16C, 16D) disposed in electrical contact with an interior of the microfluidic channel and at least one further separation electrode (16A, 16B, 16C, 16D) disposed in electrical contact with an interior of the microfluidic channel or one of the secondary microfluidic channels (4). The pair of separation electrodes (16A, 16B) are configured to pass a pulse of electrical current through the separation zone of the microfluidic channel.