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公开(公告)号：EP2780341B1
公开(公告)日：2019-02-13
申请号：EP12849393.9
申请日：2012-11-14
发明人： XIAO, Dengming , LI, Jijun , ZHU, Yan , HU, Yuandong , WANG, Huting , WANG, Zhe , WANG, Zanping , WEI, Yongheng , SUN, Yinghui , WU, Qiong , ZHANG, Hui , PENG, Yong , KONG, Fansheng , SUN, Ying , LUO, Hong , HAN, Yongxin
IPC分类号： C07D473/00 , C07D487/04 , A61K31/52 , A61P35/00 , A61K31/519 , A61P25/00 , A61P29/00 , A61P37/00
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2.发明公开KINASE MODULATING COMPOUNDS, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF 审中-公开KINASEMODULIERENDE化合物，组合物和正确使用
公开(公告)号：EP2780341A1
公开(公告)日：2014-09-24
申请号：EP12849393.9
申请日：2012-11-14
发明人： XIAO, Dengming , LI, Jijun , ZHU, Yan , HU, Yuandong , WANG, Huting , WANG, Zhe , WANG, Zanping , WEI, Yongheng , SUN, Yinghui , WU, Qiong , ZHANG, Hui , PENG, Yong , KONG, Fansheng , SUN, Ying , LUO, Hong , HAN, Yongxin
IPC分类号： C07D473/00 , C07D401/04 , A61K31/52 , A61P35/00
CPC分类号： C07D473/00 , C07D487/04
摘要： The invention provides a compound represented by formula (I) which may modulate a kinase, and a pharmaceutical composition thereof, as well as the method for preventing or treating a protein kinase mediated disease or condition.
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公开(公告)号：EP2670746A1
公开(公告)日：2013-12-11
申请号：EP12742266.5
申请日：2012-01-31
发明人： XIAO, Dengming , ZHU, Yan , HU, Yuandong , WANG, Huting , LIU, Yuliang , LI, Jijun , SUN, Deguang , WANG, Zhe , WEI, Yongheng , WANG, Zanping , TANG, Guojing , JING, Lutao
IPC分类号： C07D401/12 , C07D401/14 , C07D451/14 , A61K31/4523 , A61P43/00 , A61P3/10 , A61P3/06 , A61P3/04 , A61P3/00
CPC分类号： C07D401/04 , C07D401/12 , C07D401/14 , C07D413/14 , C07D451/14 , C07D471/04
摘要： The present invention provides a new class of bicyclic heteroaryl compounds represented by Formula (I), pharmaceutical compositions containing these compounds, and their use for modulating the activity of GPR119 in the treatment of metabolic disorders and complications thereof, as well as methods for the treatment of the metabolic disorders and complications thereof.
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