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1.发明公开ANTI-IL-12 ANTIBODY BASED VECTORS, HOST CELLS, AND METHODS OF PRODUCTION AND USES 有权ON抗体IL-12为基础的载体，宿主细胞和生产过程，并使用
公开(公告)号：EP1839120A2
公开(公告)日：2007-10-03
申请号：EP05855447.8
申请日：2005-12-21
申请人： CENTOCOR, INC.
发明人： LU, Jin , NESSPOR, Thomas , SCALLON, Bernard , SNYDER, Linda
CPC分类号： C07K16/244 , C07K16/00 , C12N15/1086 , C12N15/63
摘要： Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.
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2.发明公开
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3.发明公开ENGINEERED ANTI-TARGET IMMUNOGLOBULIN DERIVED PROTEINS, COMPOSITIONS, METHODS AND USES 审中-公开合成免疫球蛋白对目标的展望蛋白质成分，过程和应用程序的
公开(公告)号：EP1644416A2
公开(公告)日：2006-04-12
申请号：EP04776856.9
申请日：2004-06-21
申请人： CENTOCOR, INC.
发明人： LU, Jin
IPC分类号： C07K16/42
CPC分类号： C07K16/00 , C07K2317/21 , C07K2317/50
摘要： The present invention relates to anti-target immunoglobulin derived proteins, including isolated nucleic acids that encode at least one anti-target Ig derived protein, target, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
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4.发明公开
公开(公告)号：EP1539792A2
公开(公告)日：2005-06-15
申请号：EP03762033.3
申请日：2003-06-25
申请人： Centocor, Inc.
发明人： LU, Jin , HUANG, Chris , NAKADA, Marian
IPC分类号： C07H21/04 , C07K14/435 , C07K16/00 , C12N1/21 , C12N15/63 , C12N5/10 , A61K38/17 , A61K31/7088 , A61K39/395 , C12P21/00
CPC分类号： C07K14/4748 , A61K38/00
摘要： The present invention relates to at least one novel CNGH0005 polypeptides, antibodies, including isolated nucleic acids that encode at least one CNGH0005 polypeptide or antibody, CNGH0005 vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
摘要翻译： 本发明涉及至少一种新的CNGH0005多肽，抗体，包括编码至少一种CNGH0005多肽或抗体的分离的核酸，CNGH0005载体，宿主细胞，转基因动物或植物，以及其制备和使用方法，包括治疗组合物 ，方法和设备。
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公开(公告)号：EP2023962A2
公开(公告)日：2009-02-18
申请号：EP07783878.7
申请日：2007-05-17
申请人： Centocor, Inc.
发明人： DORAI, Haimanti , LU, Jin
IPC分类号： A61K51/00
CPC分类号： C07K14/4705
摘要： Homo sapiens OCT-2 variant peptide chains are disclosed. Polynucleotides encoding these peptide chains, cells comprising these polynucleotides, and methods of using the forgoing are also disclosed.
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