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公开(公告)号：EP4032560A1
公开(公告)日：2022-07-27
申请号：EP21153325.2
申请日：2021-01-25
申请人： Centre National pour la Recherche Scientifique , UNIVERSITE DE STRASBOURG , Les Hôpitaux Universitaires de Genève , UNIVERSITE DE GENEVE
发明人： DECHER, Gero , WALPOTH, Beat , FONTANA, Pierre , WITT, Maria , DE VALENCE, Sarra , TSCHOPP, Michel , FELIX, Olivier
摘要： The present invention is directed to materials compatible with blood, implantable devices comprising said material, methods of preparation of such material and medical devices coated therewith and uses thereof for anti-thrombotic and/or cell-proliferating aspects.
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公开(公告)号：EP4281130A1
公开(公告)日：2023-11-29
申请号：EP22702428.8
申请日：2022-01-24
申请人： Centre National de la Recherche Scientifique , Université de Strasbourg , Les Hôpitaux Universitaires de Genève , Université de Genève
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公开(公告)号：EP2389199A2
公开(公告)日：2011-11-30
申请号：EP10700585.2
申请日：2010-01-21
申请人： THE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , Universite De Strasbourg , Institute of Macromolecular Chemistry AS CR v.v.l.
CPC分类号： B82Y5/00 , A61K47/58 , A61K47/6923 , A61K47/6929
摘要： The present invention relates to the field of drug delivery nanosystems. More precisely, the present invention concerns a copolymer with advantageous properties for the outer coating of various nanoparticles. Said copolymer comprises at least three types of monomers with stealthy, coupling and therapeutic properties respectively, as well as an optional fourth type of monomers with targeting properties. The present invention also relates to core-shell or hollow shell nanoparticles coated by an external layer of the copolymer according to the invention. Several types of core-shell nanoparticles are envisaged. The invention also concerns methods for preparing said nanoparticles, as well as pharmaceutical compositions or medicaments comprising them.
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