公开(公告)号：EP1261623B1

公开(公告)日：2009-11-04

申请号：EP02729592.2

申请日：2002-01-10

申请人： Chebigen Inc.

发明人： SIN, Hong-Sig ,  PARK, Si-Ho ,  RHO, Young-Soy ,  UM, Soo-Jong ,  KWON, Youn-Ja ,  PARK, Myoung-Soon ,  HAN, Hye-Sook ,  JUNG, Min-Sook ,  KIM CHO, So-Mi ,  KIM, Dong-Myong ,  OH, Deok-Kun ,  PARK, Jong-Sup

IPC分类号： C07K5/00 ,  C07K5/06

CPC分类号： C07K5/06113 ,  C07K5/0613

公开(公告)号：EP1261623A1

公开(公告)日：2002-12-04

申请号：EP02729592.2

申请日：2002-01-10

申请人： Chebigen Inc.

发明人： SIN, Hong-Sig ,  PARK, Si-Ho ,  RHO, Young-Soy ,  UM, Soo-Jong ,  KWON, Youn-Ja ,  PARK, Myoung-Soon ,  HAN, Hye-Sook ,  JUNG, Min-Sook ,  KIM CHO, So-Mi ,  KIM, Dong-Myong ,  OH, Deok-Kun ,  PARK, Jong-Sup

IPC分类号： C07K5/00

CPC分类号： C07K5/06113 ,  C07K5/0613

摘要： The present invention relates to novel retinol derivatives, the methods of preparation and the uses thereof. According to the present invention, retinol derivatives comprise carboester linkage between di-, tri-, polypeptide having functional group of COOH and retinol. Retinol derivatives in the present invention comprise carboester linkage between amino acid having functional group of di-COOH and retinol. Retinol derivatives comprise carboester linkage between retinol and the compounds having the function group of COOH and multiple double bonds on carbon chain. Retinol derivatives in the present invention comprise carboester linkage between retinol and the compounds having the functional group of di-COOH and one double bond. Retinol derivatives in the present invention comprise ether linkage between the compounds with OH functional group and retinol.