公开(公告)号：EP3851435A1

公开(公告)日：2021-07-21

申请号：EP19867637.1

申请日：2019-06-05

申请人： Chinese PLA General Hospital ,  Shijiazhuang Sagacity New Drug Development Company, Ltd.

发明人： HE, Kunlun ,  GAO, Xiaojian ,  LIU, Chunlei ,  ZHANG, Zeyu ,  LI, Xin ,  LI, Chen ,  LUO, Yunfu ,  LEI, Maoyi ,  LI, Junmiao ,  WANG, Yiwei

IPC分类号： C07D405/14 ,  C07D471/04 ,  C07D417/14 ,  A61K31/506 ,  C07D491/107 ,  A61P39/00 ,  A61P11/00 ,  A61P9/00 ,  A61P9/12

摘要： The present disclosure provides application of a compound in conformity with a general formula I and an isomer or pharmaceutically acceptable salt thereof to preparation of a medicinal composition for treating or preventing a high altitude disease. The high altitude disease is selected from an acute high altitude disease and a chronic high altitude disease generated in a high altitude environment with an altitude of 2,000m or above.

公开(公告)号：EP3851106A1

公开(公告)日：2021-07-21

申请号：EP19867766.8

申请日：2019-06-05

申请人： Chinese PLA General Hospital ,  Shijiazhuang Sagacity New Drug Development Company, Ltd.

发明人： HE, Kunlun ,  ZHANG, Zeyu ,  GAO, Xiaojian ,  LIU, Chunlei ,  LI, Xin ,  LI, Chen ,  QIAN, Wenyuan ,  YANG, Chundao ,  XU, Guanghai ,  WANG, Yiwei

IPC分类号： A61K31/497 ,  C07D401/14 ,  A61P43/00

摘要： The present disclosure provides application of a compound in conformity with a general formula I, and an isomer or pharmaceutically acceptable salt thereof to preparation of a medicinal composition for treating and/or preventing a high altitude disease. The high altitude disease is selected from an acute high altitude disease or a chronic high altitude disease generated in a high altitude environment with an altitude of 2,000m or above.