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1.发明公开CYCLOALKENYL ARYL DERIVATIVES FOR CETP INHIBITOR 有权3-（2-芳基cycloalkenylmethyl）恶唑烷-2-酮化合物作为胆固醇酯转移蛋白（CETP）抑制剂
公开(公告)号：EP2697207A2
公开(公告)日：2014-02-19
申请号：EP12770951.7
申请日：2012-04-12
发明人： LEE, Seohee , OH, Jungtaek , LEE, Jaekwang , LEE, Jaewon , BAE, Suyeal , HA, Nina , LEE, Sera
IPC分类号： C07D263/16 , C07D263/22 , C07D413/06 , A61K31/421 , A61P9/00 , A61P3/06
CPC分类号： C07D263/24 , C07D263/16 , C07D263/22 , C07D401/06 , C07D413/06 , C07D413/08 , C07D413/10 , C07D417/12
摘要： The present invention relates to cycloalkenyl aryl derivatives, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof, or solvates thereof; a method for preparing the derivatives; and pharmaceutical compositions containing the same. The compounds of the present invention show the effect of CETP activity inhibition. It means that the compounds can increase HDL-cholesterol and decrease LDL-cholesterol.
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2.发明授权3-(2-ARYL-CYCLOALKENYLMETHYL)-OXAZOLIDIN-2-ONE DERIVATIVES AS CHOLESTEROL ESTER TRANSFER PROTEIN (CETP) INHIBITORS 有权3-（2-芳基cycloalkenylmethyl）恶唑烷-2-酮化合物作为胆固醇酯转移蛋白（CETP）抑制剂
公开(公告)号：EP2697207B1
公开(公告)日：2016-12-14
申请号：EP12770951.7
申请日：2012-04-12
发明人： LEE, Seohee , OH, Jungtaek , LEE, Jaekwang , LEE, Jaewon , BAE, Suyeal , HA, Nina , LEE, Sera
IPC分类号： C07D413/08 , C07D263/22 , A61K31/421 , A61P3/06 , A61P9/10
CPC分类号： C07D263/24 , C07D263/16 , C07D263/22 , C07D401/06 , C07D413/06 , C07D413/08 , C07D413/10 , C07D417/12
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