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    Application of natural mineral water with special qualities in prophylaxis hygiene and treatment of teeth and paradontium
    2.
    发明公开
    Application of natural mineral water with special qualities in prophylaxis hygiene and treatment of teeth and paradontium 有权
    Naturmineralwasser zur Prophylaxe，Hygiene und Behandlung von Zahn- und Zahnfleischerkrankungen

    公开(公告)号：EP2080438A1

    公开(公告)日：2009-07-22

    申请号：EP08460002.2

    申请日：2008-01-17

    申请人： Cieslik, Tadeusz ,  Nocon, Jacek ,  Rauch, Jan

    发明人： Cieslik, Tadeusz ,  Nocon, Jacek ,  Rauch, Jan

    IPC分类号： A23L1/304 ,  A61K33/16

    CPC分类号： A23L2/38 ,  A61K33/00 ,  A61K33/06 ,  A61K33/10 ,  A61K33/14 ,  A61K33/16 ,  A61K2300/00

    摘要： The invention refers to a new application of mineral water in prophylaxis of dental and paradontium diseases, when water has the following physiochemical and biological properties : Ph 7,6 - 8,1; electrolytic conductivity 180 - 210 µS/cm at 20°C, hardness 110 - 150 mg Ca CO 3 /l; chlorides 0,5 - 2,5 mg Cl/l; fluorides 0,01 - 0,03 mg F/l; sodium 0,6 - 1,6 mg Na/l; potassium 1,2 - 2,2 mg K/l; calcium 30 - 40 mg Ca/l; magnesium 5 - 14 mg Mg/l; faecal coli bacteria (thermotolerant) 0 in 100 ml; coli bacteria 0 in 100 ml; enterococcus 0 in 100 ml; clostridium perfrigens 0 in 100 ml; total number of bacteria at 37°C after 24 hours from 1 to 2 in 1 ml and total number of bacteria at 22°C after 72 hours from 3 to 5 in 1 ml.

    摘要翻译： 本发明涉及一种矿物水预防牙龈疾病的新应用，当水具有以下物理化学和生物学特性时：Ph 7,6 - 8,1; 电解电导率在20℃时为180-210μS/ cm，硬度为110-150mg CaCO 3 / l; 氯化物0.5-5.5mg Cl / l; 氟化物0.01-1.03mg F / l; 0-6 - 1,6 mg Na / l钠; 1,2 - 2.2 mg钾/ l; 钙30-40mg Ca / l; 镁5-14mg Mg / l; 粪便大肠杆菌（耐热菌）0在100ml中; 大肠杆菌细菌在100毫升; 肠球菌0在100毫升; 100克中的梭菌 24小时后37℃的细菌总数，1ml中的1〜2，72小时后的细菌总数，3〜5ml，1ml。

    Preparation for regeneration of post-operative and post-traumatic bone defects and method for implantation of this preparation
    4.
    发明公开
    Preparation for regeneration of post-operative and post-traumatic bone defects and method for implantation of this preparation 有权
    用于手术后和创伤后骨损伤的再生准备

    公开(公告)号：EP2080528A1

    公开(公告)日：2009-07-22

    申请号：EP08460001.4

    申请日：2008-01-17

    申请人： Cieslik, Tadeusz ,  Nocon, Jacek ,  Rauch, Jan

    发明人： Cieslik, Tadeusz ,  Nocon, Jacek ,  Rauch, Jan

    IPC分类号： A61L27/12 ,  A61L27/36

    CPC分类号： A61L27/10 ,  A61L27/12 ,  A61L27/3608 ,  A61L27/58 ,  A61L2430/02

    摘要： According to the invention preparation for regeneration of bone defects is employed in many branches of medicine, especially in orthopedics, dental surgery, reconstructive surgery, periodonthology and implantology.
    The preparation has been developed on the basis of inorganic chemical compound naturally occurring, i.e. deproteinized human bone, and on the basis of at least one of inorganic chemical compounds synthetically occurring, i.e. bioglass in the form of granulated highcalcium product (54% mol. CaO), obtained with the use of zol-gel method in the system CaO-SiO 2 -P 2 O 5 , of density 2,9082 g/cm 3 , with phase composition with a dominant glassy phase and beginnings of crystallization of apatite, heat treated at temperature of 800°C, having a specific surface BET 57,8166 m 2 /g and/or tricalcium phosphate - TCP in the form of granulated product with chemical formula Ca3 (PO 4 ) 2 . As a component deproteinized particlesof human bone are used, favourably with granulation 0,3-0,5 mm, bioglass favourably with granulation 0,3-0,5 mm and/or TCP - tricalcium phosphate favourably with granulation 0,3-0,5 mm.
    The amount of bone material in the preparation amounts favourably to 70-80% of the preparation weight, the amount of bioglass in preparation amounts favourably to 10-15% of the preparation weight, the amount of TCP in the preparation amounts favourably to 10-15% of the preparation weight.
    During implantation binder in the form of blood from patient's operative wound is introduced into the preparation. Amount of the preparation in mixture favourably amounts to 75-80% of the mixture weight and the amount of own blood favourably amounts to 20-25% of the mixture weight.

    摘要翻译： 。根据在医药的许多分支被用于骨缺损的再生本发明制剂，爱特别是在骨科，牙科手术，重建手术，periodonthology和种植。 制备已无机化学化合物的基础天然存在的，即在已经开发 脱蛋白人骨，和无机化学化合物中的至少一种的基础上发生的合成，即 生物玻璃在造粒高钙产品的形式（54％摩尔。CaO）的与系统中的CaO-SiO 2的-P 2 O 5使用唑 - 凝胶法获得10，密度2.9082克/厘米3，具有相 用显性玻璃相和磷灰石的结晶开始的组合物，在热的800℃温度下处理，具有特定表面BET57.8166米2 /克和/或磷酸三钙 - TCP在造粒产物与化学式形式 的Ca 3（PO 4）2 作为脱蛋白particlesof人骨的成分使用时，有利地与造粒0.3-0.5毫米，生物玻璃有利地与造粒0.3到0.5毫米和/或TCP - 磷酸三钙有利地与造粒0.3 0， 为5mm。 骨材料的制剂中的量优选的量加入到制剂重量的70-80％，在制备生物玻璃的量有利的量加入到制剂重量的10-15％，TCP的制剂中的量优选相当于10- 制备重量的15％。 过程中的血液从患者的外科手术伤口的形式注入粘合剂被引入到制剂。 在混合物制备的量有利的量加入到混合物重量的75-80％和自己的血液量优选量加入到混合物重量的20-25％。