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1.发明授权Hydrolysat de protéines de poissons présentant une activité de stimulation et de maintien du capital osseux, compositions nutraceutiques et pharmacologiques comprenant un tel hydrolysat et procédé d'obtention 有权Fischproteinhydrolysat与knochenstimulierender和骨保护作用，保健品和与这样的水解产物和一种用于其生产方法药物组合物，
公开(公告)号：EP2247745B1
公开(公告)日：2015-11-04
申请号：EP09711108.2
申请日：2009-02-12
CPC分类号： C07K14/461 , A23J3/346 , A23L33/18 , A23V2002/00 , A61K35/60 , A61K38/012 , C12P21/06 , A23V2250/543 , A23V2200/306
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2.发明公开HYDROLYSAT DE PROTEINES DE POISSONS POUR SON UTILISATION DANS L'INHIBITION DE LA PRISE DE POIDS ET/OU LA PERTE DE POIDS 审中-公开水解产物的鱼蛋白及其用于降低体重的增加和/或删除
公开(公告)号：EP2445360A1
公开(公告)日：2012-05-02
申请号：EP10728651.0
申请日：2010-06-25
CPC分类号： A23J3/341 , A23L17/65 , A23L33/18 , A23L33/30 , A23V2002/00 , A61K8/64 , A61K35/60 , A61K2800/91 , A61K2800/92 , A61Q19/06 , A23V2200/332 , A23V2250/543
摘要： The present invention relates to fish protein hydrolysates for the use thereof in inducing weight loss and in limiting and/or inhibiting weight gain. The invention also relates to such hydrolysates in preventing and/or treating besity and/or health problems linked to obesity. The protein hydrolysates according to the invention are obtained by the enzymatic hydrolysis of at least one protein source selected from among the group comprising the following fish:
Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina
pilchardus, Trisopterus esmarki, Trachurus spp., Gadus morhua, Pollachius virens,
Melanogrammus aeglefinus, Coryphaenoides rupestris , which belong to order Siluriformes, said enzymatic hydrolysis being performed by an endopeptidase enzyme derived from
Bacillus subtilis .-
3.发明公开HYDROLYSAT DE PROTEINES DE POISSONS PRESENTANT UNE ACTIVITE DE STIMULATION ET DE MAINTIEN DU CAPITAL OSSEUX, COMPOSITIONS NUTRACEUTIQUES ET PHARMACOLOGIQUES COMPRENANT UN TEL HYDROLYSAT ET PROCEDE D'OBTENTION 有权Fischproteinhydrolysat与knochenstimulierender和骨保护作用，保健品和与这样的水解产物和一种用于其生产方法药物组合物，
公开(公告)号：EP2247745A1
公开(公告)日：2010-11-10
申请号：EP09711108.2
申请日：2009-02-12
CPC分类号： C07K14/461 , A23J3/346 , A23L33/18 , A23V2002/00 , A61K35/60 , A61K38/012 , C12P21/06 , A23V2250/543 , A23V2200/306
摘要： The present invention relates to a fish protein hydrolysate having a biological activity of interest, in particular an effect on the stimulation and maintenance of bone. The fish protein hydrolysate is characterized in that it is obtained by enzymatic hydrolysis of at least one protein source selected from the fish species Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus, Trisopterus esmarki, Trachurus spp, Gadus morhua, Pollachius virens, Melanogrammus aeglefinus and Coryphaenoides rupestris, and the species of fish belonging to the order Siluriformes, said enzymatic hydrolysis being carried out by means of an endopeptidase enzyme derived from Bacillus subtilis. The protein hydrolysate according to the invention makes it possible to maintain the bone mass or to stimulate bone growth through stimulation of osteoblast cell growth and inhibition of osteoclast cell growth.
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4.发明公开HYDROLYSAT DE PROTEINES DE POISSONS PRESENTANT UNE ACTIVITE SATIETOGENE, COMPOSITIONS NUTRACEUTIQUES ET PHARMACOLOGIQUES COMPRENANT UN TEL HYDROLYSAT ET PROCEDE D'OBTENTION 有权Fischproteinhydrolysat与包括例如水解物，以及作为其回收方法的饱和效应，营养药物和药理学组合物
公开(公告)号：EP2247744A1
公开(公告)日：2010-11-10
申请号：EP09710311.3
申请日：2009-02-12
发明人： DRIEU LA ROCHELLE, Hubert , COUROIS, Elisa , CUDENNEC, Benoît , FOUCHEREAU-PERON, Martine , RAVALLEC-PLE, Rozenn
IPC分类号： C12P21/06 , A23J3/34 , A61K35/60 , A61K38/01 , C07K14/595
CPC分类号： A61K38/012 , A23J3/04 , A23J3/341 , A23L33/18 , A23V2002/00 , A61K35/60 , C07K14/461 , C12P21/06
摘要： The present invention relates to a fish protein hydrolysate containing molecules capable of exerting a satietogenic activity and of regulating food intake in humans or animals. More specifically, the protein hydrolysate according to the invention enables stimulation of the secretion of endogenous cholescystokinins (CCKs) and of endogenous glucagon-like peptide 1 (GLP1) molecules by intestinal cells and the supply of exogenous CCKs. The fish protein hydrolysate according to the invention is obtained by enzymatic hydrolysis of at least one protein source selected from the group composed of the pelagic fish species Micromesistius poutassou, Clupea harengus, Scomber scombrus, Sardina pilchardus, Trisopterus esmarki and Trachurus spp., the demersal fish species Gadus morhua, Pollachius virens, Melanogrammus aeglefinus and Coryphaenoides rupestris, and the species of fish belonging to the order Siluriformes, said enzymatic hydrolysis being carried out by means of a mixture of enzymes comprising endopeptidases derived from Bacillus amyloliquefaciens and from Bacillus licheniformis, or derived from Bacillus amyloliquefaciens, from Bacillus licheniformis and from Aspergillus oryzae.
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