公开(公告)号：EP2635663B1

公开(公告)日：2019-05-08

申请号：EP11785851.4

申请日：2011-11-03

申请人： Corbion Biotech, Inc.

发明人： FRANKLIN, Scott ,  LU, Wenhua ,  RAKITSKY, Walter ,  RODRIGUEZ, Felipe Arana ,  RUDENKO, George ,  WEE, Janice ,  ZHAO, Xinhua

IPC分类号： C11B1/02 ,  C12P7/64 ,  H01B3/22 ,  H01F27/12

公开(公告)号：EP2670855B1

公开(公告)日：2019-08-21

申请号：EP12741997.6

申请日：2012-02-02

申请人： Corbion Biotech, Inc.

发明人： FRANKLIN, Scott ,  SOMANCHI, Aravind ,  WEE, Janice ,  RUDENKO, George ,  MOSELEY, Jeffrey ,  RAKITSKY, Walt ,  ZHAO, Xinhua ,  BHAT, Riyaz

IPC分类号： C12N1/13 ,  C12N9/02 ,  C12N9/10 ,  C12N9/16 ,  C12N15/52 ,  C12P7/64

公开(公告)号：EP3523425A2

公开(公告)日：2019-08-14

申请号：EP17791781.2

申请日：2017-10-05

申请人： Corbion Biotech, Inc.

发明人： MOSELEY, Jeffrey L. ,  CASOLARI, Jason ,  ZHAO, Xinhua ,  EWING, Aren ,  SOMANCHI, Aravind ,  FRANKLIN, Scott ,  DAVIS, David

IPC分类号： C12N9/10

公开(公告)号：EP3521408A1

公开(公告)日：2019-08-07

申请号：EP18212337.2

申请日：2011-11-03

申请人： Corbion Biotech, Inc.

发明人： FRANKLIN, Scott ,  LU, Wenhua ,  RAKITSKY, Walter ,  RODRIGUEZ, Felipe Arana ,  RUDENKO, George ,  WEE, Janice ,  ZHAO, Xinhua

IPC分类号： C11B1/02 ,  C12P7/64 ,  H01B3/22 ,  H01F27/12 ,  C12N9/16

摘要： Methods and compositions for the production of dielectric fluids from lipids produced by microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a lipid pathway modification enzyme, a fatty acyl-ACP thioesterase, a desaturase, a fatty acyl-CoA/aldehyde reductase, and/or an acyl carrier protein are useful in manufacturing dielectric fluids.

公开(公告)号：EP2839018B1

公开(公告)日：2019-06-05

申请号：EP13778920.2

申请日：2013-04-18

申请人： Corbion Biotech, Inc.

发明人： FRANKLIN, Scott ,  SOMANCHI, Aravind ,  RUDENKO, George ,  BHAT, Riyaz ,  ZHAO, Xinhua ,  BOND, Risha ,  RAKITSKY, Walter ,  MARANGONI, Alejandro ,  BRAKSMAYER, Diza

IPC分类号： C12P7/64

公开(公告)号：EP3550025A1

公开(公告)日：2019-10-09

申请号：EP19172300.6

申请日：2013-04-18

申请人： Corbion Biotech, Inc.

发明人： FRANKLIN, Scott ,  SOMANCHI, Aravind ,  RUDENKO, George ,  BHAT, Riyaz ,  ZHAO, Xinhua ,  BOND, Risha ,  RAKITSKY, Walter ,  MARANGONI, Alejandro ,  BRAKSMAYER, Diza

IPC分类号： C12P7/64

摘要： Recombinant DNA techniques are used to produce oleaginous recombinant cells that produce triglyceride oils having desired fatty acid profiles and regiospecific or stereospecific profiles. Genes manipulated include those encoding stearoyl-ACP desturase, delta 12 fatty acid desaturase, acyl-ACP thioesterase, ketoacyl-ACP synthase, and lysophosphatidic acid acyltransferase. The oil produced can have enhanced oxidative or thermal stability, or can be useful as a frying oil, shortening, roll-in shortening, tempering fat, cocoa butter replacement, as a lubricant, or as a feedstock for various chemical processes. The fatty acid profile can be enriched in midchain profiles or the oil can be enriched in triglycerides of the saturated-unsatturated-saturated type.