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公开(公告)号:EP2118065B1
公开(公告)日:2013-08-14
申请号:EP07849684.1
申请日:2007-11-30
发明人: QAZI, Ghulam, Nabi , SAXENA, Ajit, Kumar , MUTHIAH, Shanmugavel , MONDHE, Dilip, Manikrao , SHARMA, Parduman, Raj , SINGH, Shashank, Kumar , SANYAL, Utpal , MUKHERJEE, Asama , HAZRA, Suva , DUTTA, Susanta
IPC分类号: C07D221/14 , A61K31/473 , A61P35/00
CPC分类号: C07D221/14
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公开(公告)号:EP2118065A1
公开(公告)日:2009-11-18
申请号:EP07849684.1
申请日:2007-11-30
发明人: QAZI, Ghulam, Nabi , SAXENA, Ajit, Kumar , MUTHIAH, Shanmugavel , MONDHE, Dilip, Manikrao , SHARMA, Parduman, Raj , SINGH, Shashank, Kumar , SANYAL, Utpal , MUKHERJEE, Asama , HAZRA, Suva , DUTTA, Susanta
IPC分类号: C07D221/14 , A61K31/473 , A61P35/00
CPC分类号: C07D221/14
摘要: The present invention relates to novel substituted 1H-benz[de]isoquinoline-1,3-diones. This invention particularly relates to novel substituted 1H-benz[de]isoquinoline-1,3-diones particularly N-[2-(Chloroethyl)]- and N-[3-(Chloropropyl)]-naphthalimides and antitumor activity thereof. The present invention also relates to process of preparation of novel substituted 1H-benz[de]isoquinoline-1,3-diones. The present invention further relates to pharmaceutical composition for the treatment of cancer and related diseases.
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