公开(公告)号：EP1549671A2

公开(公告)日：2005-07-06

申请号：EP03726154.2

申请日：2003-04-01

申请人： Curagen Corporation

发明人： ALSOBROOK, John, P. II ,  BENTO, Patricia ,  BOLDOG, Ferenc, L. ,  BURGESS, Catherine, E. ,  CASMAN, Stacie, J. ,  CRABTREE-BOKOR, Julie, R. ,  EDINGER, Shlomit, R. ,  ELLERMAN, Karen ,  FERNANDES, Elma, R. ,  GERLACH, Valerie, L. ,  GROSSE, William M. ,  GUNTHER, Erik ,  GUSEV, Vladimir, Y. ,  HEYES, Melvyn, P. ,  LEPLEY, Denise, M. ,  LI, Li ,  MACDOUGALL, John, R. ,  MALYANKAR, Uriel, M. ,  MILLET, Isabelle ,  PATTURAJAN, Meera ,  PEYMAN, John A. ,  RASTELLI, Luca ,  RIEGER, Daniel K. ,  SHENOY, Suresh G. ,  SHIMKETS, Richard D. ,  SMITHSON, Glennda ,  STONE, David J. ,  VERNET, Corine A.M. ,  VOSS, Edward Z.

IPC分类号： C07K14/00 ,  A61K38/17 ,  G01N33/53

CPC分类号： C07K14/47 ,  A61K38/00

摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.