-
公开(公告)号：EP2121007A1
公开(公告)日：2009-11-25
申请号：EP07858126.1
申请日：2007-12-21
发明人： HUBER, Adrian , BACHMANN, Martin , JENNINGS, Gary , TISSOT, Alain , LANGEDIJK, Johannes , TIMMERMAN, Peter , SLOOTSTRA, Jelle , BOSHUIZEN, Ronald
CPC分类号： A61K39/0005 , A61K39/12 , A61K39/21 , A61K2039/5258 , A61K2039/54 , A61K2039/545 , A61K2039/60 , A61K2039/6075 , A61K2039/62 , A61K2039/64 , C12N2740/16011 , C12N2740/16034 , C12N2795/18123 , C12N2795/18142
摘要： The present invention is in the fields of medicine, public health, immunology, molecular biologyand virology. The invention provides composition comprising a virus-like particle (VLP) linked to atleast one antigen, wherein said antigen is CCR5 PNt domain comprising one looped peptidic structure. The invention also provides a process for producing the composition. The compositions ofthis invention are useful in the production of vaccines, in particular, for the prevention and treatment of HIV infection. Moreover, the compositions of the invention induce efficient immune responses, in particular antibody responses.
-
2.发明公开ANTIGEN ARRAYS PRESENTING IL-5, IL-13 OR EOTAXIN FOR TREATMENT OF ALLERGIC EOSINOPHILIC DISEASES 有权抗原网格，其IL-5，IL-13或嗜伊红素目前，对于过敏性的治疗，嗜酸性粒细胞疾病
公开(公告)号：EP1443960A2
公开(公告)日：2004-08-11
申请号：EP02802656.5
申请日：2002-11-07
IPC分类号： A61K39/39
CPC分类号： A61K39/35 , A61K38/00 , A61K39/0007 , A61K39/39 , A61K47/6901 , A61K2039/5256 , A61K2039/5258 , A61K2039/6075 , A61K2039/627 , C07K14/005 , C07K14/523 , C07K14/5409 , C07K14/5437 , C07K16/00 , C07K16/082 , C07K16/22 , C07K16/2863 , C07K16/40 , C07K16/4291 , C07K2317/52 , C07K2317/55 , C07K2319/00 , C07K2319/30 , C12N2730/10122
摘要： The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an array comprising a protein or peptide of IL-5, IL-13 or eotaxin. More specifically, the invention provides a composition comprising a virus-like particle and at least one protein, or peptide of IL-5, IL-13 and/or eotaxin bound thereto. The invention also provides a process for producing the conjugates and the ordered and repetitive arrays, respectively. The compositions of the invention are useful in the production of vaccines for the treatment of allergic diseases with an eosinophilic component and as a pharmaccine to prevent or cure allergic diseases with an eosinophilic component and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context.
-
公开(公告)号：EP2231179A2
公开(公告)日：2010-09-29
申请号：EP08864811.8
申请日：2008-12-22
发明人： BACHMANN, Martin , JENNINGS, Gary , RÖHN, Till
CPC分类号： C07K16/22 , A61K2039/5258 , A61K2039/6075 , A61K2039/62 , C07K14/48 , C07K2317/73 , C12N7/00 , C12N2795/00023 , C12N2795/18123
摘要： The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides composition comprising a virus-like particle (VLP) linked to at least one antigen, wherein said antigen is NGF antigen. The invention also provides a process for producing the composition. The compositions of this invention are useful in the production of vaccines, in particular, for the treatment of pain. Moreover, the compositions of the invention induce efficient immune responses, in particular antibody responses.
-
4.发明授权ANTIGEN ARRAYS PRESENTING IL-5, IL-13 OR EOTAXIN FOR TREATMENT OF ALLERGIC EOSINOPHILIC DISEASES 有权抗原网格，其IL-5，IL-13或嗜伊红素目前，对于过敏性的治疗，嗜酸性粒细胞疾病
公开(公告)号：EP1443960B1
公开(公告)日：2008-12-31
申请号：EP02802656.5
申请日：2002-11-07
IPC分类号： A61K39/39
CPC分类号： A61K39/35 , A61K38/00 , A61K39/0007 , A61K39/39 , A61K47/6901 , A61K2039/5256 , A61K2039/5258 , A61K2039/6075 , A61K2039/627 , C07K14/005 , C07K14/523 , C07K14/5409 , C07K14/5437 , C07K16/00 , C07K16/082 , C07K16/22 , C07K16/2863 , C07K16/40 , C07K16/4291 , C07K2317/52 , C07K2317/55 , C07K2319/00 , C07K2319/30 , C12N2730/10122
-
公开(公告)号：EP1784210A2
公开(公告)日：2007-05-16
申请号：EP05810942.2
申请日：2005-08-04
CPC分类号： C07K7/06 , A61K39/0006 , A61K39/0011 , A61K39/39 , A61K2039/5258 , A61K2039/55516 , A61K2039/6075 , C07K7/08 , C07K7/23
摘要： The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising a virus like particle (VLP) and at least one GnRH peptide or fragment or variant thereof linked thereto. The invention also provides a process for producing the composition. The compositions of the invention are useful in the production of vaccines for the treatment of GnRH-related diseases and conditions and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self- specific immune responses within the indicated context.
-
-
-
-
搜索结果
5 条记录 (耗时 0.02 秒)
