公开(公告)号：EP1623976A4

公开(公告)日：2008-07-30

申请号：EP04729271

申请日：2004-04-23

申请人： DAICEL CHEM

发明人： KUDO KEIKO ,  TACHIBANA KOZO ,  MURAZUMI KOICHI

IPC分类号： C07D209/24 ,  B01D15/18 ,  B01D15/38 ,  B01J20/285 ,  B01J20/286 ,  C07B57/00 ,  C07D209/12

CPC分类号： C07D209/24 ,  B01D15/1821 ,  B01D15/3833 ,  B01J20/285 ,  B01J20/286 ,  B01J20/3272 ,  B01J20/328 ,  C07B2200/07 ,  C07D209/12

摘要： An optically active dihydroxyheptenoic acid ester having an aromatic group is separated from a solution containing a mixture of optical isomers of the dihydroxyheptenoic acid ester by liquid chromatography with a packing material constituted of a carrier and a polysaccharide derivative supported on the carrier. The polysaccharide derivative is a polysaccharide in which the hydrogen atoms constituting the hydroxyl and amino groups are partially or all replaced by one or more kinds of groups selected from among carbamoyl groups monosubstituted with aromatic groups having specific alkyl groups and benzoyl groups having specific alkyl groups. According to the invention, optically active dihydroxyheptenoic acid esters can be separated more distinctly.

公开(公告)号：EP1637542A4

公开(公告)日：2007-04-04

申请号：EP04729279

申请日：2004-04-23

申请人： DAICEL CHEM

发明人： ONISHI ATSUSHI ,  KUDO KEIKO

IPC分类号： C08B15/00 ,  B01J20/285 ,  B01J20/29 ,  C08B15/06 ,  C08B33/00

CPC分类号： B01J20/262 ,  B01J20/265 ,  B01J20/285 ,  B01J20/29 ,  C08B15/06

摘要： A separatory agent for optical isomers which contains a polysaccharide derivative as an active ingredient, wherein the polysaccharide derivative serving as an active ingredient is one formed by replacing at least part of the hydrogen atoms of the hydroxy groups and amino groups of a polysaccharide with at least one member selected between a benzoyl group having a specific alkyl group and a carbamoyl group in which one hydrogen atom has been replaced with an aromatic group having a specific alkyl group. It is a novel separatory agent for optical isomers which has the high ability to asymmetrically identify the target compound to be analyzed and isolated.