摘要:
A cassette assembly comprising a blood flow path through which blood is drawn from a patient and passed through a dialyzer. The blood flow path includes a blood flow pump. The cassette assembly comprises at least two cassettes. The assembly also comprises a dialysate flow path through which dialysate flows from a dialysate supply through the dialyzer. The dialysate flow path includes a dialysate pump. The dialysate flow path is defined by the at least two cassettes that are immobilized relative to each other. The assembly further comprises a pod pump connectable between the two cassettes, and a control fluid path through which a control fluid actuates the blood flow pump and the dialysate pump.
摘要:
A membrane-based valve comprising a top plate (214), a bottom plate (216) and a midplate (204) located between the top plate and the bottom plate, with a flexible membrane (202) interposed between the top plate and midplate. The top plate includes a pneumatic port (208) configured to deliver pneumatic pressure to the membrane. The midplate includes an inlet (218) and an outlet (220) in fluid communication with the membrane. The valve further comprises a valve seat (210). The bottom plate further comprises fluid paths defining the inlet and the outlet. The membrane and top plate define a control gas chamber (212), and the membrane and midplate define a valving chamber (206), the inlet and outlet in communication with the valving chamber (206) via holes formed through the midplate (204). A thickened rim (222) of the membrane is configured to be held in a groove (224) in the midplate. A cross-sectional shape of a part of the membrane comprises a first region with a cross-sectional curvature in a first direction that is a direction toward the top plate and a second region located within the first region with a cross-sectional curvature in a second direction opposite the first direction, and the pneumatic pressure from the pneumatic port is configured to force the membrane against the valve seat to close the valve, or draw the membrane away from the valve seat to open the valve.
摘要:
A system for monitoring fluid flow in an extracorporeal blood circuit comprising: a pumping chamber of a blood pump separated from a control chamber of the blood pump by a flexible diaphragm, the control chamber configured to transmit positive or negative pressure to operate the diaphragm; a pressure sensor configured to measure pressure in the control chamber of the blood pump; a controller configured to receive information from the pressure sensor, and configured to control the delivery of pressure to the control chamber of the blood pump; wherein the controller is configured to cause an application of a time-varying pressure waveform on the blood pump diaphragm during a fill-stroke of the blood pump, and to monitor a pressure variation in the control chamber measured by the pressure sensor, and wherein the controller is configured to determine a blood flow metric based on a variation of a peak-to-peak magnitude and to alert a user based on the blood flow metric.
摘要:
A medical infusion fluid handling system, such as an APD system, may be arranged to de-cap and connect one or more lines (30) (such as solution lines) with one or more spikes (160) or other connection ports on a fluid handling cassette (24). This feature may reduce a likelihood of contamination since no human interaction is required to de-cap and connect the lines and spikes. For example, an APD system may include a carriage (146) arranged to receive a plurality of solution lines (30) each having a connector end (31a) and a cap (31). The carriage may move along a first direction so as to move the connector ends of the solution lines along the first direction, and a cap stripper (149) may be arranged to engage with caps on the solution lines on the carriage. The cap stripper may move in a second direction transverse to the first direction, as well as to move with the carriage along the first direction.
摘要:
A pump cassette comprising a midplate interposed between a top plate and a bottom plate, the midplate comprising: a first port on a first end of the midplate connected to a first fluid channel, and a second port on a second end of the midplate connected to a second fluid channel, each said fluid channel defined by the midplate and the top plate; a pump, comprising a flexible pump diaphragm configured to cover an aperture in the midplate, the pump diaphragm separating a pumping chamber between the pump diaphragm and the top plate from an actuation chamber between the pump diaphragm and the bottom plate; and an inlet valve and an outlet valve, each valve comprising two valve ports connecting a first side of the midplate facing the top plate with a second side of the midplate facing the bottom plate, a flexible valve diaphragm configured to cover the two valve ports and to separate a valve actuation chamber between the valve diaphragm and the bottom plate from a valve fluid chamber between the valve diaphragm and the midplate; wherein a first valve port of the inlet valve is connected to the first fluid channel, and a second valve port of the inlet valve is connected to an inlet of the pumping chamber, and a first valve port of the outlet valve is connected to the second fluid channel and a second valve port of the outlet valve is connected to an outlet of the pumping chamber.
摘要:
There is disclosed herein a system for adjusting a negative pressure used to withdraw fluid from a cavity of a patient, the system comprising: a pump configured to provide negative or positive pressure to a fluid line connected to the cavity; a controller configured to measure and control the pressure provided by the pump; the controller (61100) also configured to measure a flow rate of fluid from the fluid line to the pump; wherein the controller (61100) is arranged to control the pump by providing negative pressure to the fluid line, measuring the rate of fluid flow, and control the pump by providing a positive pressure to the fluid line if the measured rate of fluid flow is less than a pre-determined value; and wherein the controller (61100) is arranged to re-apply negative pressure to the fluid line if a measured fluid flow upon application of the positive pressure is greater than a pre-determined amount.
摘要:
A fluid handling cassette for use in a medical infusion system, the cassette comprising: a generally planar body having first and second pump chambers each formed as a depression in a first side of the body, each pump chamber having a first port and a second port connecting the respective pump chamber to a second side of the body; a plurality of valve wells on the first side of the body including first and second groups of valve wells, valve wells in the first group of valve wells each comprising a valve port and an opening connecting a respective valve well to the second side of the body; valve wells in the second group of valve wells each comprising a valve port connecting a respective valve well to the second side of the body, and each fluidly connected to a respective one of a plurality of cassette ports located on a first end of the body; and a first and second fluid flowpath on the second side of the body, each fluid flowpath connected to the first or second port of a respective pump chamber via at least one valve well of the first group of valve wells; wherein the first and second fluid flowpaths are each connected to at least one of the plurality of cassette ports via a respective valve well of the second group of valve wells.
摘要:
A dialysate delivery set comprising: a fluid handling cassette for use in a peritoneal dialysis system, the cassette comprising: a generally planar body having a first and a second pump chamber formed as a depression in a first side of the body and having a first and a second opening fluidly connected to first and second channels, respectively; a patient line port arranged for connection to a patient line for delivering dialysate to the peritoneal cavity of a patient, the patient line port being in fluid communication with the first and second pump chambers via the second channel; a drain line port arranged for connection to a drain line for draining dialysate from the peritoneal cavity of a patient, the drain line port being in fluid communication with the first and second chambers via the first channel; a heater bag line port arranged for connection to a heater bag line, the heater bag line port in fluid communication with the first and second pump chambers via the first channel; a plurality of solution line spikes being in fluid communication with the first and second pump chambers via the first channel; and a flexible membrane attached to the first side of the body over the first and second pump chambers, a pump chamber portion of the membrane over the first and second pump chambers being arranged to be movable for movement of fluid in the pump chambers; the patient line fluidly connected to the patient line port; the drain line fluidly connected to the drain line port; and a heater bag and the heater bag line fluidly connected to the heater bag line port.
摘要:
An occluder (147), and methods for occlusion, that employs first and second opposed occluding members (165) associated with each other, a tube contacting member (161) connected to, or comprising at least portion of, at least one of the first and second occluding members, and a force actuator (166) constructed and positioned to apply a force to at least one of the first and second occluding members. Application of the force by the force actuator may cause the tube contacting member to move between a tube occluding and an open position. A release member (169) may be configured and positioned to enable an operator to manually move the tube contacting member from the tube occluding position to the open position even with no force applied to the occluding member by the force actuator. In one embodiment, the force actuator may apply a force sufficient to bend both the first and second occluding members, so that upon application of the force by the force actuator (such as an air bladder), the first and second occluding members (e.g., spring plates pivotal Iy connected at opposite ends) bend and the tube contacting member may move between a tube occluding and an open position.