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Patent Agency Ranking
公开(公告)号：EP3395876A1
公开(公告)日：2018-10-31
申请号：EP18174672.8
申请日：2007-09-05
Applicant: DSM IP Assets B.V.
Inventor： ARMES, Steven , YUAN, Jian-Jun
CPC classification number: A61K9/5089 , A61K9/501 , C08K3/36 , C08K9/00 , C08K9/02 , C08K9/10 , C08K9/12 , C08K2201/011 , C08K2201/013 , C08L53/00 , C08L2207/53 , C09D7/70 , G02B1/111 , Y10T428/254 , Y10T428/2998
Abstract: The invention provides a composition comprising core-shell nanoparticles, the nanoparticles comprising
(a) cationic core material comprising polymer; and
(b) a shell material comprising silica.
Preferred core materials comprise diblock copolymer micelles comprising one block of dialkylaminoethyl methacrylate units which are partially or fully quaternised and one block of dialkylaminoethyl methacrylate units that remain non-quaternised .
The invention also provides a method for the preparation of the said composition, the method involving
(a) preparing a cationic core material comprising polymer; and
(b) coating the core material with a shell comprising silica by treating the polymer with a silica precursor under ambient conditions.
The invention also envisages a composition comprising core-shell nanoparticles which is adapted to facilitate controlled delivery of at least one active agent into a system in response to controlled changes in the pH of the system.-
公开(公告)号：EP3483638A1
公开(公告)日：2019-05-15
申请号：EP18213801.6
申请日：2007-09-05
Applicant: DSM IP Assets B.V.
Inventor： ARFSTEN, Nanning Joerg , ARMES, Steven , BUSKENS, Pascal Jozef Paul , THIES, Jens Christoph , VRIJALDENHOVEN, Patrick Wilhelmus Antonius
Abstract: The present invention relates to a composition suitable for forming an optical coating, the composition comprising core-shell nanoparticles, wherein said nanoparticles comprise:
(a) core material comprising polymer; and
(b) shell material comprising metal oxide.-
公开(公告)号：EP2059558A2
公开(公告)日：2009-05-20
申请号：EP07802136.7
申请日：2007-09-05
Applicant: DSM IP Assets B.V.
Inventor： ARMES, Steven , YUAN, Jian-Jun
CPC classification number: A61K9/5089 , A61K9/501 , C08K3/36 , C08K9/00 , C08K9/02 , C08K9/10 , C08K9/12 , C08K2201/011 , C08K2201/013 , C08L53/00 , C08L2207/53 , C09D7/70 , G02B1/111 , Y10T428/254 , Y10T428/2998
Abstract: The invention provides a composition comprising core-shell nanoparticles, the nanoparticles comprising (a) cationic core material comprising polymer; and (b) a shell material comprising silica. Preferred core materials comprise diblock copolymer micelles comprising one block of dialkylaminoethyl methacrylate units which are partially or fully quaternised and one block of dialkylaminoethyl methacrylate units that remain non-quaternised. The invention also provides a method for the preparation of the said composition, the method involving (a) preparing a cationic core material comprising polymer; and (b) coating the core material with a shell comprising silica by treating the polymer with a silica precursor under ambient conditions. The invention also envisages a composition comprising core-shell nanoparticles which is adapted to facilitate controlled delivery of at least one active agent into a system in response to controlled changes in the pH of the system.
Abstract translation: 本发明提供包含核 - 壳纳米颗粒的组合物，所述纳米颗粒包含（a）包含聚合物的阳离子核心材料; 和（b）包含二氧化硅的壳材料。 优选的核心材料包括二嵌段共聚物胶束，其包含部分或全部季铵化的一个二烷基氨基乙基甲基丙烯酸酯单元和一个保持非季铵化的一个二烷基氨基乙基甲基丙烯酸酯单元。 本发明还提供了制备所述组合物的方法，所述方法包括（a）制备包含聚合物的阳离子核心材料; 和（b）在环境条件下用二氧化硅前体处理聚合物，用包含二氧化硅的壳涂覆芯材料。 本发明还设想了包含核 - 壳纳米颗粒的组合物，其适于响应于系统的pH的受控变化而促进至少一种活性剂被控制递送到系统中。
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公开(公告)号：EP2059558B1
公开(公告)日：2018-10-24
申请号：EP07802136.7
申请日：2007-09-05
Applicant: DSM IP Assets B.V.
Inventor： ARMES, Steven , YUAN, Jian-Jun
CPC classification number: A61K9/5089 , A61K9/501 , C08K3/36 , C08K9/00 , C08K9/02 , C08K9/10 , C08K9/12 , C08K2201/011 , C08K2201/013 , C08L53/00 , C08L2207/53 , C09D7/70 , G02B1/111 , Y10T428/254 , Y10T428/2998
Abstract: The invention provides a composition comprising core-shell nanoparticles, the nanoparticles comprising (a) cationic core material comprising polymer; and (b) a shell material comprising silica. Preferred core materials comprise diblock copolymer micelles comprising one block of dialkylaminoethyl methacrylate units which are partially or fully quaternised and one block of dialkylaminoethyl methacrylate units that remain non-quaternised . The invention also provides a method for the preparation of the said composition, the method involving (a) preparing a cationic core material comprising polymer; and (b) coating the core material with a shell comprising silica by treating the polymer with a silica precursor under ambient conditions. The invention also envisages a composition comprising core-shell nanoparticles which is adapted to facilitate controlled delivery of at least one active agent into a system in response to controlled changes in the pH of the system.
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公开(公告)号：EP2059836A2
公开(公告)日：2009-05-20
申请号：EP07802135.9
申请日：2007-09-05
Applicant: DSM IP Assets B.V.
Inventor： ARFSTEN, Nanning, Joerg , ARMES, Steven , BUSKENS, Pascal, Jozef, Paul , THIES, Jens, Christoph , VRIJALDENHOVEN, Patrick, Wilhelmus, Antonius
CPC classification number: A61K9/5089 , A61K9/501 , C08K3/36 , C08K9/00 , C08K9/02 , C08K9/12 , C08K2201/013 , C08L53/00 , C09D7/70 , G02B1/111 , Y10T428/254 , Y10T428/2998
Abstract: The invention provides a composition comprising core-shell nanoparticles, the nanoparticles comprising (a) cationic core material comprising polymer; and (b) a shell material comprising silica. Preferred core materials comprise diblock copolymer micelles comprising one block of dialkylaminoethyl methacrylate units which are partially or fully quaternised and one block of dialkylaminoethyl methacrylate units that remain non-quaternised. The invention also provides a method for the preparation of the said composition, the method involving (a) preparing a cationic core material comprising polymer; and (b) coating the core material with a shell comprising silica by treating the polymer with a silica precursor under ambient conditions. The invention also envisages a composition comprising core-shell nanoparticles which is adapted to facilitate controlled delivery of at least one active agent into a system in response to controlled changes in the pH of the system.
Abstract translation: 本发明提供包含核 - 壳纳米颗粒的组合物，所述纳米颗粒包含（a）包含聚合物的阳离子核心材料; 和（b）包含二氧化硅的壳材料。 优选的核心材料包括二嵌段共聚物胶束，其包含部分或全部季铵化的一个二烷基氨基乙基甲基丙烯酸酯单元和一个保持非季铵化的一个二烷基氨基乙基甲基丙烯酸酯单元。 本发明还提供了制备所述组合物的方法，所述方法包括（a）制备包含聚合物的阳离子核心材料; 和（b）在环境条件下用二氧化硅前体处理聚合物，用包含二氧化硅的壳涂覆芯材料。 本发明还设想了包含核 - 壳纳米颗粒的组合物，其适于响应于系统的pH的受控变化而促进至少一种活性剂被控制递送到系统中。
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