专利检索 ap:("Daegu-Gyeongbuk Medical Innovation Foundation" OR "Immunoforge Co., Ltd.") AND inv:"JEONG, Myeong-Sook" 第 1 页

1.

发明公开
3-((8-((1H-PYRAZOL-4-YL)AMINO)IMIDAZO[1,2-A]PYRIDIN-3-YL)ETHINYL)-N-PHENYLBENZAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER 审中-公开

公开(公告)号：EP4105217A1

公开(公告)日：2022-12-21

申请号：EP21761078.1

申请日：2021-02-26

申请人： Daegu-Gyeongbuk Medical Innovation Foundation , Immunoforge Co., Ltd.

发明人： LEE, Doohyun , LEE, Seungyeon , HAN, Ye Ri , IM, Chun Young , KIM, So Young , KIM, Nam Hui , CHOI, Hwan Geun , KO, Eunhwa , MOON, Heegyum , LEE, Sun Joo , KIM, Sang Bum , KIM, Hyo-Ji , LEE, Sion , AHN, Sung-Min , CHANG, Kiho , LEE, Eunkyu , KWON, Hyun Jin , JEONG, Myeong-Sook , KIM, Ji Young

IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61K31/496 , A61P35/00 , A23L33/10

摘要： The present invention relates to a 3-((8-((1H-pyrazol-4-yl)amino)imidazo[1,2-a]pyridin-3-yl)ethynyl)-N-phenylbenzamide derivative, a method for preparing the same, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating cancer. The derivative can significantly inhibit the proliferation of cancer cells by inhibiting kinases, particularly Bcr-Abl kinase or Bcr-Abl (T315I) kinase. Therefore, the derivative can be effectively used as a pharmaceutical composition for the prevention or treatment of cancer.