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公开(公告)号：EP3789493A1
公开(公告)日：2021-03-10
申请号：EP19796874.6
申请日：2019-04-11
IPC分类号： C12P19/00
摘要： A method for producing a cellooligosaccharide that enables the formation of a cellooligosaccharide having a high degree of polymerization to be suppressed in enzymatic synthesis of a cellooligosaccharide, the method comprising reacting α-glucose-1-phosphate and at least one primer selected from the group consisting of glucose, cellobiose, and alkylated glucose with cellodextrin phosphorylase in a mixed solvent containing water and a water-soluble organic solvent.
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公开(公告)号：EP4053141A1
公开(公告)日：2022-09-07
申请号：EP20880549.9
申请日：2020-10-23
摘要： To culture cells in a suspended state and easily recover the cultured cells. An additive for suspension culture according to an embodiment is a medium additive which is added to a medium for culturing cells in suspension, the medium additive containing a cellulose oligomer. A medium composition according to an embodiment is a medium composition capable of culturing cells in suspension, the medium composition containing a cellulose oligomer. A cell culture method according to an embodiment includes culturing cells in the medium composition.
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3.发明公开
公开(公告)号：EP3954698A1
公开(公告)日：2022-02-16
申请号：EP20784736.9
申请日：2020-03-03
摘要： The present invention provides a biocompatible material improved in biocompatibility owing to adsorption of a peptide that has high adhesion with a resin and hardly separates from a surface of the resin, and a functional material including the biocompatible material. The biocompatible material (10) includes a resin (1) and a peptide (2) adsorbed on the resin (1). The resin (1) has methoxycarbonyl groups and methyl groups, and tryptophan or arginine accounts for 70% or more of amino acid residues in the peptide (2) . As an alternative, the resin 1 is a fluorinated resin, and 2,3,4,5,6-pentafluoro-phenylalanine, 3-(trifluoromethyl)alanine, serine, threonine, histidine, aspartic acid, glutamic acid, phenylalanine, or aspartic acid accounts for 40% or more of the amino acid residues in the peptide (2). The functional material includes the biocompatible material (10), and a functional substance. The functional substance is held on a surface of the biocompatible material (10) or is released from the surface of the biocompatible material (10).
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公开(公告)号：EP3872176A1
公开(公告)日：2021-09-01
申请号：EP19874976.4
申请日：2019-10-17
摘要： This invention provides a novel carrier for enzyme immobilization and an immobilized enzyme. The carrier for enzyme immobilization according to an embodiment comprises a porous material and cellulose that has an amino group-containing substituent at an anomeric position and is immobilized on the porous material. The immobilized enzyme contains the carrier for enzyme immobilization and an enzyme immobilization on the cellulose. The carrier for enzyme immobilization is obtained by adding an acid to an aqueous solution in which cellulose having an amino group-containing substituent at an anomeric position is dissolved in an aqueous alkaline solution to deposit the cellulose in the presence of a porous material. The immobilized enzyme is obtained by immobilizing an enzyme on the cellulose.
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