公开(公告)号：EP0990632A1

公开(公告)日：2000-04-05

申请号：EP99917071.5

申请日：1999-04-21

申请人： Daicel Chemical Industries, Ltd.

发明人： NAKANO, Tatsuya ,  SHIMOJITOSYO, Hiroshi

IPC分类号： C07C31/137 ,  C07C31/27 ,  C07C35/37 ,  C07C29/143 ,  C07C29/147 ,  C07C43/196 ,  C07C41/26

CPC分类号： C07C31/278 ,  C07C31/137 ,  C07C43/315 ,  C07C2603/74 ,  Y02P20/55

摘要： An adamantanemethanol derivative of the invention is represented by the following formula (1), wherein R a is a hydrogen atom or a hydrocarbon group; R b is a hydrocarbon group having a carbon atom, to which carbon atom at least one hydrogen atom is bonded, at a bonding site with the adjacent carbon atom; R c , R d and R e are each a hydrogen atom, a hydroxyl group which may be protected by a protective group or the like; provided that a hydroxyl group protected by a protective group or the like is bonded to at least one carbon atom constituting the adamantane skeleton when R a is a hydrogen atom or a methyl group and R b is a methyl group; and at least one substituent, in addition to the HO-C(R a )(R b )- group indicated in the formula (1), is bonded to the adamantane ring when one of R a and R b is a methyl group and the other is an ethyl group.

摘要翻译： 本发明的金刚烷甲醇衍生物由下式（1）表示，其中R a是氢原子或烃基; R b是在与相邻碳原子的键合位置处具有与碳原子键合至少一个氢原子的碳原子的烃基; R c，R d和R e各自为氢原子，可被保护基等保护的羟基; 条件是当R a为氢原子或甲基且R b为甲基时，由保护基等保护的羟基与构成金刚烷骨架的至少一个碳原子键合; 并且除了式（1）中所示的HO-C（R a）（R））基团之外，至少一个取代基与R a和R R之一键合到金刚烷环上 b是甲基，另一个是乙基。

公开(公告)号：EP1070699A1

公开(公告)日：2001-01-24

申请号：EP00902030.6

申请日：2000-02-01

申请人： Daicel Chemical Industries, Ltd.

发明人： NAKANO, Tatsuya ,  SHIMOJITOSYO, Hiroshi

IPC分类号： C07C31/137 ,  C07C35/23 ,  C07C35/37 ,  C07C29/143 ,  C07C29/147 ,  C07C69/54

CPC分类号： C07C69/72 ,  C07C31/137 ,  C07C35/37 ,  C07C35/40 ,  C07C43/315 ,  C07C45/45 ,  C07C45/71 ,  C07C49/323 ,  C07C49/345 ,  C07C49/35 ,  C07C69/013 ,  C07C69/54 ,  C07C2602/10 ,  C07C2603/24 ,  C07C2603/68 ,  Y02P20/55

摘要： Hydroxymethyl-containing alicyclic compounds represented by formula (1) or (2), wherein rings A, B, C, D, and E each represents a nonaromatic carbon ring; R a and R b each represents hydrogen or a hydrocarbon group and at least one of R a and R b is a hydrocarbon group; and R c , R d , and R e each represents hydrogen, halogeno, alkyl, hydroxyl optionally protected by a protective group, hydroxymethyl optionally protected by a protective group, amino optionally protected by a protective group, carboxyl optionally protected by a protective group, nitro, acyl, or a group represented by formula (3) (wherein R a and R b have the same meanings as the above).

摘要翻译： 含羟甲基由下式表示的脂环化合物（1）或（2），worin环A，B，C，D，和E各自darstellt一个非芳族碳环; RA和RB的每个darstellt氢或烃基，R和R中的至少一个的是烃基; 且R - [R 和R 每个darstellt氢，卤素，烷基，被保护基任意保护的羟基，被保护基任意保护的羟基甲基，氨基任选地被保护基保护，羧基OPTIONALLY 被保护基团，硝基，酰基，或由式所示的基团保护的（3）（R worin a和R的具有相同的含义同上）。