公开(公告)号：EP1350511B1

公开(公告)日：2008-09-10

申请号：EP01271850.8

申请日：2001-12-20

申请人： Daiichi Sankyo Company, Limited ,  Ube Industries, Ltd.

发明人： ASAI, Fumitoshi ,  SUGIDACHI, Atsuhiro ,  OGAWA, Taketoshi ,  INOUE, Teruhiko

IPC分类号： A61K31/4365 ,  A61K31/60

CPC分类号： A61K45/06 ,  A61K31/4365 ,  A61K31/60 ,  A61K31/616 ,  A61K2300/00

摘要： Medicinal compositions containing as the active ingredients 2-acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine or its pharmacologically acceptable salt and aspirin. Because of having excellent inhibitory effects on platelet aggregation and thrombosis, these compositions are useful as preventives or remedies for diseases induced by thrombus or embolization.

公开(公告)号：EP1350511A1

公开(公告)日：2003-10-08

申请号：EP01271850.8

申请日：2001-12-20

申请人： Sankyo Company, Limited ,  Ube Industries, Ltd.

发明人： ASAI, Fumitoshi ,  SUGIDACHI, Atsuhiro ,  OGAWA, Taketoshi ,  INOUE, Teruhiko

IPC分类号： A61K31/4365 ,  A61K31/616 ,  A61P7/02

CPC分类号： A61K45/06 ,  A61K31/4365 ,  A61K31/60 ,  A61K31/616 ,  A61K2300/00

摘要： [Subject]
Pharmaceutical compositions comprising 2-acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine or a pharmaceutically acceptable salt thereof, and aspirin, as active ingredients.
[Effect]
The pharmaceutical compositions of the present invention possess excellent inhibitory activity against platelet aggregation and thrombogenesis, and are useful for preventing or treating diseases caused by thrombus or embolus.

摘要翻译： 包含2-乙酰氧基-5-（α-环丙基羰基-2-氟苄基）-4,5,6,7-四氢噻吩并[3,2-c]吡啶或其药学上可接受的盐和作为活性成分的阿司匹林的药物组合物。 本发明的药物组合物对血小板聚集和血栓形成具有优异的抑制活性，可用于预防或治疗由血栓或栓塞引起的疾病。