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公开(公告)号:EP3416958A1
公开(公告)日:2018-12-26
申请号:EP17753951.7
申请日:2017-02-17
申请人: Dana Farber Cancer Institute, Inc. , President and Fellows of Harvard College , The General Hospital Corporation
发明人: WAGNER, Gerhard , ARTHANARI, Haribabu , NÄÄR, Anders , BUHRLAGE, Sara Jean , NISHIKAWA, Joy Luz , BOESZOERMENYI, Andras Pal , SANGLARD, Dominique
IPC分类号: C07D401/12 , C07D231/40
CPC分类号: C07D295/26 , C07C337/06 , C07C2601/02 , C07C2601/14 , C07D311/16 , C07D317/66 , C07D333/70
摘要: Provided herein are compounds (e.g., compounds of Formulae (I), (II), and (III)) which are anti-fungal agents and can be used in the treatment of diseases, including infectious diseases. The invention provides methods of treating diseases in a subject (e.g., infectious diseases such as fungal infections), and methods of killing or inhibiting the growth of fungi in or on a subject or biological sample. The compounds may be used in subjects, in clinical settings, or in agricultural settings.