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公开(公告)号:EP3164221A1
公开(公告)日:2017-05-10
申请号:EP15814884.1
申请日:2015-06-24
申请人: Dance Biopharm Inc.
发明人: FINK, Jim , MOLLOY, Lisa , MACLOUGHLIN, Ronan , LILLIS, Clair Elizabeth , CASEY, Michael Joseph , MULLINS, John Matthew , HYLAND, Kieran James , GREHAN, Joseph Martin , SMITH, Niall Scott
IPC分类号: B05B1/08
摘要: Embodiments provide aerosolization device for providing aerosolized medicament to user. The aerosolization device includes conduit, aerosol generator, fluid receiving chamber, restrictor within the conduit, and indicator mechanism. Conduit has an inner wall and a mouthpiece end for causing an inspiratory flow. Aerosol generator includes a vibratable mesh laterally offset from the inner wall. Fluid receiving chamber receives liquid medicament. At least a portion of chamber is tapered such that liquid medicament is directed onto vibratable mesh for aerosolization. Restrictor defines a plurality of apertures that provide increases in pressure differential that vary with inspiratory flow rate within conduit and provide relatively laminar flow downstream of restrictor. Indicator mechanism indicates a state of flow parameters relative to a predefined range. Aerosol generator is configured to aerosolize at least a portion of liquid medicament only when flow parameters of the inspiratory flow are within range.
摘要翻译: 实施例提供用于向使用者提供雾化药物的雾化装置。 雾化装置包括导管,气溶胶发生器,流体接收室,导管内的限流器和指示器机构。 导管有一个内壁和一个吸嘴端,用于引起吸气流。 气溶胶发生器包括从内壁横向偏移的可振动网。 流体接收室接收液体药物。 腔室的至少一部分是锥形的,使得液体药剂被引导到可振动网上用于雾化。 限流器限定多个孔,其提供随着管道内的吸气流率而变化的压差增大并且提供限流器下游的相对层流。 指示器机制指示相对于预定范围的流量参数的状态。 气溶胶发生器构造成仅当吸气流量的流量参数在范围内时才使至少一部分液体药剂雾化。
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公开(公告)号:EP3164222B1
公开(公告)日:2019-03-20
申请号:EP15816007.7
申请日:2015-06-24
申请人: Dance Biopharm Inc.
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公开(公告)号:EP3164221B8
公开(公告)日:2019-12-18
申请号:EP15814884.1
申请日:2015-06-24
申请人: Dance BioPharm Inc.
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公开(公告)号:EP3164221B1
公开(公告)日:2019-11-06
申请号:EP15814884.1
申请日:2015-06-24
申请人: Dance Biopharm Inc.
发明人: FINK, Jim , MOLLOY, Lisa , MACLOUGHLIN, Ronan , LILLIS, Clair Elizabeth , CASEY, Michael Joseph , MULLINS, John Matthew , HYLAND, Kieran James , GREHAN, Joseph Martin , SMITH, Niall Scott
摘要: Embodiments provide aerosolization device for providing aerosolized medicament to user. The aerosolization device includes conduit, aerosol generator, fluid receiving chamber, restrictor within the conduit, and indicator mechanism. Conduit has an inner wall and a mouthpiece end for causing an inspiratory flow. Aerosol generator includes a vibratable mesh laterally offset from the inner wall. Fluid receiving chamber receives liquid medicament. At least a portion of chamber is tapered such that liquid medicament is directed onto vibratable mesh for aerosolization. Restrictor defines a plurality of apertures that provide increases in pressure differential that vary with inspiratory flow rate within conduit and provide relatively laminar flow downstream of restrictor. Indicator mechanism indicates a state of flow parameters relative to a predefined range. Aerosol generator is configured to aerosolize at least a portion of liquid medicament only when flow parameters of the inspiratory flow are within range.
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公开(公告)号:EP3164222A1
公开(公告)日:2017-05-10
申请号:EP15816007.7
申请日:2015-06-24
申请人: Dance Biopharm Inc.
发明人: FINK, Jim , MOLLOY, Lisa , MACLOUGHLIN, Ronan , LILLIS, Claire Elizabeth , CASEY, Michael Joseph , MULLINS, John Matthew , HYLAND, Kieran James , GREHAN, Joseph Martin
IPC分类号: B05B1/08
CPC分类号: A61M15/002 , A61M11/005 , A61M15/0021 , A61M15/0085 , A61M2016/0021 , A61M2016/0027 , A61M2016/003 , A61M2205/3331 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/584 , A61M2205/6018 , A61M2205/6054 , A61M2205/6072 , A61M2205/8206 , A61M2206/11
摘要: In one aspect, embodiments of the present invention provide an aerosolization device for ensuring proper delivery of an aerosolized medication to a user's respiratory system. The aerosolization device may include a conduit, an aerosol generator, a restrictor disposed within the conduit, and an indicator mechanism. The conduit may include a mouthpiece end by which a user may cause inspiratory flow through the conduit. The aerosol generator may include a vibratable mesh. The restrictor may define a plurality of apertures disposed along an outer periphery of the restrictor configured to provide an increase in pressure differential that varies with an inspiratory flow rate within the conduit and to provide a relatively laminar flow downstream of the restrictor compared to upstream of the restrictor. The indicator mechanism may indicate to a user a state of a parameter of the inspiratory flow relative to a predefined desired range.
摘要翻译: 在一个方面,本发明的实施例提供了一种雾化装置,用于确保雾化药物向用户的呼吸系统的正确输送。 雾化装置可以包括导管,气溶胶发生器,设置在导管内的限流器和指示器机构。 导管可以包括吸嘴端,通过该吸嘴端使用者可以引起通过导管的吸气流。 气雾剂发生器可以包括可振动网。 限流器可限定沿限流器的外周布置的多个孔,所述多个孔被配置成提供随着管道内的吸气流速而变化的压差的增加,并且与限流器的上游相比提供限流器下游的相对层流 限流器。 指示器机构可以向用户指示吸气流量的参数相对于预定义的期望范围的状态。
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