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    LIQUID NEBULIZATION SYSTEMS AND METHODS
    2.
    发明公开
    LIQUID NEBULIZATION SYSTEMS AND METHODS 有权
    液体雾化系统和方法

    公开(公告)号：EP3164221A1

    公开(公告)日：2017-05-10

    申请号：EP15814884.1

    申请日：2015-06-24

    申请人： Dance Biopharm Inc.

    发明人： FINK, Jim ,  MOLLOY, Lisa ,  MACLOUGHLIN, Ronan ,  LILLIS, Clair Elizabeth ,  CASEY, Michael Joseph ,  MULLINS, John Matthew ,  HYLAND, Kieran James ,  GREHAN, Joseph Martin ,  SMITH, Niall Scott

    IPC分类号： B05B1/08

    摘要： Embodiments provide aerosolization device for providing aerosolized medicament to user. The aerosolization device includes conduit, aerosol generator, fluid receiving chamber, restrictor within the conduit, and indicator mechanism. Conduit has an inner wall and a mouthpiece end for causing an inspiratory flow. Aerosol generator includes a vibratable mesh laterally offset from the inner wall. Fluid receiving chamber receives liquid medicament. At least a portion of chamber is tapered such that liquid medicament is directed onto vibratable mesh for aerosolization. Restrictor defines a plurality of apertures that provide increases in pressure differential that vary with inspiratory flow rate within conduit and provide relatively laminar flow downstream of restrictor. Indicator mechanism indicates a state of flow parameters relative to a predefined range. Aerosol generator is configured to aerosolize at least a portion of liquid medicament only when flow parameters of the inspiratory flow are within range.

    摘要翻译： 实施例提供用于向使用者提供雾化药物的雾化装置。 雾化装置包括导管，气溶胶发生器，流体接收室，导管内的限流器和指示器机构。 导管有一个内壁和一个吸嘴端，用于引起吸气流。 气溶胶发生器包括从内壁横向偏移的可振动网。 流体接收室接收液体药物。 腔室的至少一部分是锥形的，使得液体药剂被引导到可振动网上用于雾化。 限流器限定多个孔，其提供随着管道内的吸气流率而变化的压差增大并且提供限流器下游的相对层流。 指示器机制指示相对于预定范围的流量参数的状态。 气溶胶发生器构造成仅当吸气流量的流量参数在范围内时才使至少一部分液体药剂雾化。

    LIQUID DISPENSING AND METHODS FOR DISPENSING LIQUIDS
    4.
    发明公开
    LIQUID DISPENSING AND METHODS FOR DISPENSING LIQUIDS 审中-公开
    液体分配和液体分配方法

    公开(公告)号：EP2986268A1

    公开(公告)日：2016-02-24

    申请号：EP14785659.5

    申请日：2014-04-16

    申请人： Dance Biopharm Inc.

    发明人： PATTON, John S. ,  PATTON, Ryan S. ,  MOLLOY, Lisa ,  FINK, Jim

    IPC分类号： A61J1/20 ,  A61J1/22 ,  A61M15/00 ,  B65D83/42

    CPC分类号： A61M15/0065 ,  A61M11/005 ,  A61M15/0085 ,  A61M2202/0468 ,  A61M2207/00 ,  A61M2209/045 ,  B05B11/0037 ,  B05B11/00444 ,  B05B17/0646

    摘要： A dispenser for supplying a metered volume of a liquid medicament to an aerosolizing device. The dispenser may include a container having a proximal end and a distal end, wherein the container is configured to store a volume of liquid medicament. The dispenser may also include a dispensing mechanism coupled to the distal end of the container. The dispensing mechanism may have a distal end terminating in a tip through which the liquid medicament is dispensed. The dispensing mechanism operates to dispense a metered volume of the liquid medicament from the tip each time the dispensing mechanism is operated. The distal end of the dispensing mechanism includes an interface that interacts with a housing of an inhaler to limit an insertion depth of the tip into an opening the housing.

    摘要翻译： 用于将计量体积的液体药剂供应到雾化装置的分配器。 分配器可以包括具有近端和远端的容器，其中容器构造成存储一定体积的液体药物。 分配器还可以包括联接到容器的远端的分配机构。 分配机构可以具有终止于尖端的远端，液体药剂通过该尖端被分配。 每次分配机构被操作时，分配机构操作以从尖端分配计量体积的液体药物。 分配机构的远端包括界面，该界面与吸入器的壳体相互作用以限制尖端插入壳体的开口中的插入深度。

    LIQUID NEBULIZATION SYSTEMS
    6.
    发明授权
    LIQUID NEBULIZATION SYSTEMS 有权

    公开(公告)号：EP3164221B1

    公开(公告)日：2019-11-06

    申请号：EP15814884.1

    申请日：2015-06-24

    申请人： Dance Biopharm Inc.

    发明人： FINK, Jim ,  MOLLOY, Lisa ,  MACLOUGHLIN, Ronan ,  LILLIS, Clair Elizabeth ,  CASEY, Michael Joseph ,  MULLINS, John Matthew ,  HYLAND, Kieran James ,  GREHAN, Joseph Martin ,  SMITH, Niall Scott

    IPC分类号： A61M11/00 ,  A61M15/00 ,  B05B1/08

    摘要： Embodiments provide aerosolization device for providing aerosolized medicament to user. The aerosolization device includes conduit, aerosol generator, fluid receiving chamber, restrictor within the conduit, and indicator mechanism. Conduit has an inner wall and a mouthpiece end for causing an inspiratory flow. Aerosol generator includes a vibratable mesh laterally offset from the inner wall. Fluid receiving chamber receives liquid medicament. At least a portion of chamber is tapered such that liquid medicament is directed onto vibratable mesh for aerosolization. Restrictor defines a plurality of apertures that provide increases in pressure differential that vary with inspiratory flow rate within conduit and provide relatively laminar flow downstream of restrictor. Indicator mechanism indicates a state of flow parameters relative to a predefined range. Aerosol generator is configured to aerosolize at least a portion of liquid medicament only when flow parameters of the inspiratory flow are within range.

    LIQUID DRUG CARTRIDGES AND ASSOCIATED DISPENSER
    10.
    发明公开
    LIQUID DRUG CARTRIDGES AND ASSOCIATED DISPENSER 审中-公开
    FLUSIIGZNEIMITTELKARTUSCHEN UNDZUGEHÖRIGERSPENDER

    公开(公告)号：EP3151891A1

    公开(公告)日：2017-04-12

    申请号：EP15806485.7

    申请日：2015-06-08

    申请人： Dance Biopharm Inc.

    发明人： STEDMAN, Benjamin ,  FINK, Jim ,  MOLLOY, Lisa ,  SANDER, Matt

    IPC分类号： A61M11/00

    摘要： Liquid drug cartridges and an associated inhaler are used to deliver one more separate doses of an aerosolized liquid drug. A cartridge includes a container for storing the liquid drug, an end cap having an ejection opening, a filter element, and a piston that is repositionable relative to the container to selectively eject a volume of liquid drug from the ejection opening. The filter element filters the liquid drug prior to ejection from the ejection opening. The liquid drug cartridge can be coupled with an inhaler that includes an aerosol generator. The aerosol generator includes a vibratable membrane onto which the liquid drug is ejected. The liquid drug is aerosolized by the vibration of the membrane for inhalation by a user.

    摘要翻译： 自我穿刺液体药物药筒和相关联的吸入器用于递送另外一个剂量的雾化液体药物。 药筒包括联接到药物容器的针组件。 针组件包括中空针，并且在将药筒插入吸入器中时可从第一配置重新配置到第二配置。 在第一构造中，中空针不延伸到容器中。 在第二构造中，中空针延伸到容器中。 吸入器包括气溶胶发生器，其包括可振动的膜，其使从药筒喷出的液体药物雾化，由患者吸入。