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公开(公告)号:EP2523716B1
公开(公告)日:2020-11-11
申请号:EP11733286.6
申请日:2011-01-12
申请人: Dance BioPharm Inc.
发明人: PATTON, John S. , PATTON, Ryan S. , KUO, Mei-chang , IVRI, Yehuda
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公开(公告)号:EP2986268B1
公开(公告)日:2019-05-22
申请号:EP14785659.5
申请日:2014-04-16
申请人: Dance Biopharm Inc.
发明人: PATTON, John S. , PATTON, Ryan S. , MOLLOY, Lisa , FINK, Jim
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公开(公告)号:EP3261648A1
公开(公告)日:2018-01-03
申请号:EP15883637.9
申请日:2015-12-21
申请人: Dance Biopharm Inc.
CPC分类号: A61K38/28 , A61K9/0073
摘要: Liquid formulations of insulin that contain physically and chemically stable insulin but do not contain preservatives or stabilizers are provided. The formulations also lack surfactants. The formulations are useful for various modes of delivery including pulmonary delivery.
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公开(公告)号:EP2986268A1
公开(公告)日:2016-02-24
申请号:EP14785659.5
申请日:2014-04-16
申请人: Dance Biopharm Inc.
发明人: PATTON, John S. , PATTON, Ryan S. , MOLLOY, Lisa , FINK, Jim
CPC分类号: A61M15/0065 , A61M11/005 , A61M15/0085 , A61M2202/0468 , A61M2207/00 , A61M2209/045 , B05B11/0037 , B05B11/00444 , B05B17/0646
摘要: A dispenser for supplying a metered volume of a liquid medicament to an aerosolizing device. The dispenser may include a container having a proximal end and a distal end, wherein the container is configured to store a volume of liquid medicament. The dispenser may also include a dispensing mechanism coupled to the distal end of the container. The dispensing mechanism may have a distal end terminating in a tip through which the liquid medicament is dispensed. The dispensing mechanism operates to dispense a metered volume of the liquid medicament from the tip each time the dispensing mechanism is operated. The distal end of the dispensing mechanism includes an interface that interacts with a housing of an inhaler to limit an insertion depth of the tip into an opening the housing.
摘要翻译: 用于将计量体积的液体药剂供应到雾化装置的分配器。 分配器可以包括具有近端和远端的容器,其中容器构造成存储一定体积的液体药物。 分配器还可以包括联接到容器的远端的分配机构。 分配机构可以具有终止于尖端的远端,液体药剂通过该尖端被分配。 每次分配机构被操作时,分配机构操作以从尖端分配计量体积的液体药物。 分配机构的远端包括界面,该界面与吸入器的壳体相互作用以限制尖端插入壳体的开口中的插入深度。
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公开(公告)号:EP2523712B1
公开(公告)日:2018-08-22
申请号:EP11733287.4
申请日:2011-01-12
申请人: Dance Biopharm Inc.
发明人: PATTON, John S. , PATTON, Ryan S. , KUO, Mei-chang , IVRI, Yehuda
CPC分类号: A61M15/0028 , A61K9/0073 , A61K9/122 , A61K33/30 , A61K38/28 , A61M11/00 , A61M11/001 , A61M11/005 , A61M15/0021 , A61M15/0065 , A61M15/0085 , A61M15/009 , A61M15/0091 , A61M2016/0021 , A61M2016/0039 , A61M2202/0468 , A61M2205/3334 , A61M2205/583 , A61M2205/587
摘要: One embodiment describes an insulin formulation that is specifically adapted for aerosolization. The formulation includes a major amount of water and a minor amount of insulin. Further, the formulation is preservative free, without meta-cresol, cresol or phenol, to permit the formulation to be aerosolized using a vibrating aperture plate without substantial foaming of the insulin formulation.
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