公开(公告)号：EP2084273A1

公开(公告)日：2009-08-05

申请号：EP07837430.3

申请日：2007-08-29

申请人： Danisco US, Inc., Genencor Division

发明人： AEHLE, Wolfgang ,  ESTELL, David A. ,  HOMMES, Ronaldus W.J. ,  JONES, Brian E. ,  KOLKMAN, Marc ,  LEEFLANG, Chris ,  OH, Hiroshi ,  POULOSE, Ayrookaran J. ,  SHAW, Andrew ,  VAN DER KLEIJ, Wilhelmus A. H. ,  VAN MARREWIJK, Leo

IPC分类号： C12N9/52 ,  C12N15/52 ,  C12N15/63

CPC分类号： C12N9/52 ,  A23K20/189 ,  A23K50/75 ,  C11D3/386 ,  C12N9/96 ,  C12Y304/21 ,  D06M16/003

摘要： The present invention provides Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.