专利检索 ap:("Davidson, Clifford M." OR "AGRICULTURAL RESEARCH ORGANIZATION, MINISTRY OF AGRICULTURAL, STATE OF ISRAEL" OR "HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT CO. LTD., KIRYAT HADASSAH") AND inv:"VLODAVSKY, Israel" 第 1 页

1.

发明公开
QUINAZOLINONE PHARMACEUTICALS AND USE THEREOF 失效
标题翻译：喹唑啉酮药物及其用途

公开(公告)号：EP0787000A1

公开(公告)日：1997-08-06

申请号：EP95933731.0

申请日：1995-08-29

申请人： Davidson, Clifford M. , AGRICULTURAL RESEARCH ORGANIZATION, MINISTRY OF AGRICULTURAL, STATE OF ISRAEL , HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT CO. LTD., KIRYAT HADASSAH

发明人： NAGLER, Arnon , SLAVIN, Shimon , VLODAVSKY, Israel , PINES, Mark

IPC分类号： C07D401 , A61K31 , A61P9 , A61P43

CPC分类号： A61K31/517

摘要： The invention provides a pharmaceutical composition for preventing restenosis by the inhibition of vascular smooth muscle cell proliferation, comprising a compound of formula (I) wherein: R1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy; R2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy, and R3 is a member of the group consisting of hydrogen and lower alkenoxy-carbonyl as active ingredient therein, in combination with a pharmaceutically acceptable carrier.

2.

发明公开
QUINAZOLINONE-CONTAINING PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE USE THEREOF 失效
标题翻译：喹唑啉酮药物遏制和使用方法

公开(公告)号：EP0794780A1

公开(公告)日：1997-09-17

申请号：EP95944408.0

申请日：1995-12-21

申请人： Davidson, M. Clifford , AGRICULTURAL RESEARCH ORGANIZATION, MINISTRY OF AGRICULTURAL, STATE OF ISRAEL , HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT COMPANY, LTD.

发明人： NAGLER, Arnon , SLAVIN, Shimon , VLODAVSKY, Israel , PINES, Mark

IPC分类号： C07D401 , A61K31 , A61P43

CPC分类号： A61K31/4545

摘要： The invention provides a composition for attenuating mesangial cell proliferation, comprising an amount of a compound of formula (I) wherein: R1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy; R2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy, and R3 is a member of the group consisting of hydrogen and lower alkenoxy-carbonyl; effective to attenuate mesangial cell proliferation.