公开(公告)号：EP1914209A1

公开(公告)日：2008-04-23

申请号：EP06122489.5

申请日：2006-10-18

申请人： Degussa Novara Technology S.p.A.

发明人： Giardino, Vincenzo ,  Gini, Lucia

IPC分类号： C03C1/00 ,  C03C4/00 ,  C01B33/16

CPC分类号： C03C3/097 ,  C03C1/006 ,  C03C4/0007 ,  C03C2201/06 ,  C03C2201/28 ,  C03C2201/54 ,  C03C2203/22

摘要： An improved sol-gel process is disclosed for the making of large synthetic silica based bioactive materials objects crack-free. A series of ordered mesoporous SiO 2 -CaO-P 2 O 5 sol-gel glasses which are highly bioactive has been synthesized through a sol-gel process. The mesoporous glasses are highly bioactive compared with conventional ones, due to the increased textural characteristics i.e. surface area. The bioactivity tests point out that the surface area, porosity, and 3D-structure become more important than chemical composition during the apatite crystallization stage in these materials, due to the very high textural parameters obtained. The product is intended to be used for tissue engineering applications.

摘要翻译： 公开了一种改进的溶胶 - 凝胶方法，用于制造大的合成二氧化硅基生物活性材料物体无裂纹。 已经通过溶胶 - 凝胶法合成了一系列有序介孔SiO 2 -CaO-P 2 O 5溶胶凝胶玻璃，其具有高度的生物活性。 由于增加的结构特征，即表面积，介孔玻璃与常规玻璃相比具有高生物活性。 生物活性测试指出，由于获得的非常高的结构参数，表面积，孔隙率和3D结构在这些材料中的磷灰石结晶阶段期间比化学成分更重要。 该产品旨在用于组织工程应用。