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公开(公告)号:EP1378515A1
公开(公告)日:2004-01-07
申请号:EP02014074.5
申请日:2002-07-01
IPC分类号: C07K11/00
CPC分类号: C07K7/08 , A61K38/00 , C07K14/001 , C07K14/4747
摘要: The present invention relates to peptides which interact with IAPs. IAPs are highly expressed in tumor cells which fail to undergo apoptosis. By binding to IAPs, the peptides of the present invention release tumor cells from the apoptosis block and thus provide a new tool for effective cancer therapy.
摘要翻译: 本发明涉及与IAP相互作用的肽。 IAP在不能进行细胞凋亡的肿瘤细胞中高度表达。 通过结合IAP,本发明的肽从凋亡阻断区释放肿瘤细胞,从而提供有效的癌症治疗的新工具。
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公开(公告)号:EP1795538A1
公开(公告)日:2007-06-13
申请号:EP06122212.1
申请日:2003-07-01
IPC分类号: C07K11/00
CPC分类号: C07K7/08 , A61K38/00 , C07K14/001 , C07K14/4747
摘要: The present invention relates to peptides which interact with IAPs. IAPs are highly expressed in tumor cells which fail to undergo apoptosis. By binding to IAPs, the peptides of the present invention release tumor cells from the apoptosis block and thus provide a new tool for effective cancer therapy.
摘要翻译: 本发明涉及与IAP相互作用的肽。 IAP在不能进行细胞凋亡的肿瘤细胞中高度表达。 通过结合IAP,本发明的肽从凋亡阻断区释放肿瘤细胞,从而提供有效的癌症治疗的新工具。
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