公开(公告)号：EP1019726A1

公开(公告)日：2000-07-19

申请号：EP96938587.1

申请日：1996-11-06

申请人： Diabact AB

发明人： HEDNER, Jan ,  PETTERSSON, Anders

IPC分类号： G01N33/569 ,  C12Q1/04 ,  A61K45/00

CPC分类号： A61K31/00 ,  G01N33/56922 ,  G01N2333/205 ,  Y10S436/90

摘要： A method for identification of an infant being particularly susceptible to sudden infant death syndrome (SIDS) comprises the determination of an Helicobacter pylori infection in the infant's mother, particularly by detection of antibodies to H. pylori of the IgG type, in a blood sample drawn from the infant's mother or by determination of carbon dioxide formed from urea in the air exhaled from the infant's mother upon oral administration of a challenge dose of urea. Also disclosed is the use of an antibiotic effective against H. pylori for the manufacture of a medicament for administration to mothers and other persons infected by H. pylori and coming into close bodily contact with infants below two years of age, and a method for prevention of SIDS by administration of that antibiotic.

公开(公告)号：EP1019726B1

公开(公告)日：2002-02-13

申请号：EP96938587.1

申请日：1996-11-06

申请人： Diabact AB

发明人： HEDNER, Jan ,  PETTERSSON, Anders

IPC分类号： G01N33/569 ,  C12Q1/04 ,  A61K45/00

CPC分类号： A61K31/00 ,  G01N33/56922 ,  G01N2333/205 ,  Y10S436/90

摘要： A method for identification of an infant being particularly susceptible to sudden infant death syndrome (SIDS) comprises the determination of an Helicobacter pylori infection in the infant's mother, particularly by detection of antibodies to H. pylori of the IgG type, in a blood sample drawn from the infant's mother or by determination of carbon dioxide formed from urea in the air exhaled from the infant's mother upon oral administration of a challenge dose of urea. Also disclosed is the use of an antibiotic effective against H. pylori for the manufacture of a medicament for administration to mothers and other persons infected by H. pylori and coming into close bodily contact with infants below two years of age, and a method for prevention of SIDS by administration of that antibiotic.