公开(公告)号：EP4501346A1

公开(公告)日：2025-02-05

申请号：EP23189833.9

申请日：2023-08-04

Applicant: Dompe' Farmaceutici S.P.A.

Inventor： BRANDOLINI, Laura ,  GIORGIO, Cristina ,  ARAMINI, Andrea ,  ALLEGRETTI, Marcello ,  DETTA, Nicola ,  ROMEO, Tiziana ,  FETONI, Anna Rita

IPC: A61K38/18 ,  A61K8/04 ,  A61P25/00 ,  A61P27/16

Abstract: The present invention relates to brain derived nerve factor (BDNF) for use in the prevention of a hearing loss induced by a platinum-based chemotherapy drug in a subject, wherein said BDNF is administered intratympanically to said subject.

公开(公告)号：EP4342485A1

公开(公告)日：2024-03-27

申请号：EP22197562.6

申请日：2022-09-23

Applicant: Dompe' Farmaceutici S.P.A.

Inventor： ALLEGRETTI, Marcello ,  ARAMINI, Andrea ,  BRANDOLINI, Laura ,  CATTANI, Franca ,  MANTELLI, Flavio

IPC: A61K38/18 ,  A61P21/02 ,  A61K9/00

Abstract: The present invention relates to nerve growth factor (NGF) or a mutein thereof for use in the prevention or treatment of spasticity in a subject, wherein preferably said NGF or mutein is administered intranasally to said subject.

公开(公告)号：EP3900715A1

公开(公告)日：2021-10-27

申请号：EP20170737.9

申请日：2020-04-21

Applicant: Dompe' Farmaceutici S.P.A.

Inventor： ARAMINI, Andrea ,  ALLEGRETTI, Marcello ,  BIANCHINI, Gianluca ,  LILLINI, Samuele ,  TOMASSETTI, Mara ,  BRANDOLINI, Laura

IPC: A61K31/192 ,  A61K31/195 ,  A61P25/04 ,  A61P29/00

Abstract: The present invention relates to a synergistic admixture of Gabapentin and Ketoprofen, preferably Ketoprofen Lysine, to a pharmaceutical composition comprising said admixtures and to the use of said admixtures or pharmaceutical compositions in the treatment of acute or chronic pain, in particular in the treatment of neuropathic or inflammatory pain.

公开(公告)号：EP4397306A1

公开(公告)日：2024-07-10

申请号：EP23150466.3

申请日：2023-01-05

Applicant: Dompe' Farmaceutici S.P.A.

Inventor： SCHMIDT, Enno ,  LUDWIG, Ralf ,  PATZELT, Sabrina ,  ARAMINI, Andrea ,  BRANDOLINI, Laura ,  COCCHIARO, Pasquale ,  BIANCHINI, Gianluca ,  DETTA, Nicola

IPC: A61K31/426 ,  A61K31/155 ,  A61K31/166 ,  A61K31/40 ,  A61K31/445 ,  A61P17/00 ,  A61P27/02 ,  A61P27/12 ,  A61P37/00 ,  A61K31/404 ,  A61K31/4453 ,  A61K39/395

CPC classification number: A61P27/02 ,  A61P27/12 ,  A61P17/00 ,  A61P37/00 ,  A61K31/445 ,  A61K31/155 ,  A61K31/166 ,  A61K31/40 ,  A61K31/426 ,  A61K31/404 ,  A61K31/4453 ,  C07K16/2896 ,  A61K2039/50520130101 ,  A61K2039/5420130101 ,  A61K2039/5520130101 ,  A61K2039/54520130101

Abstract: The invention relates to C5aRl inhibitors for use in the prevention and/or treatment of ocular mucous membrane pemphigoid and/or oral mucous membrane pemphigoid.

公开(公告)号：EP4397305A1

公开(公告)日：2024-07-10

申请号：EP23150423.4

申请日：2023-01-05

Applicant: Dompe' Farmaceutici S.P.A.

Inventor： SCHMIDT, Enno ,  LUDWIG, Ralf ,  PATZELT, Sabrina ,  ARAMINI, Andrea ,  BRANDOLINI, Laura ,  COCCHIARO, Pasquale ,  BIANCHINI, Gianluca ,  DETTA, Nicola

IPC: A61K31/18 ,  A61K31/4164 ,  A61K31/421 ,  A61K31/426 ,  A61K31/573 ,  A61P17/00 ,  A61P27/02 ,  A61P37/00

CPC classification number: A61P27/02 ,  A61P17/00 ,  A61P37/00 ,  A61K31/18 ,  A61K31/4164 ,  A61K31/421 ,  A61K31/426 ,  A61K31/573

Abstract: The invention relates to CXCL8 inhibitors useful in the prevention and/or treatment of ocular mucous membrane pemphigoid and/or oral mucous membrane pemphigoid.

公开(公告)号：EP4169903A1

公开(公告)日：2023-04-26

申请号：EP21204515.7

申请日：2021-10-25

Applicant: Dompe' Farmaceutici S.P.A.

Inventor： ARAMINI, Andrea ,  BIANCHINI, Gianluca ,  LILLINI, Samuele ,  TOMASSETTI, Mara ,  BRANDOLINI, Laura

IPC: C07C229/26 ,  C07C57/30 ,  C07C229/28 ,  A61P29/00

Abstract: The present invention relates to new co-crystals of non-steroidal anti-inflammatory drugs (NSAIDs) belonging to the class of phenylpropionic or phenylacetic acid derivatives, Lysine and Gabapentin, to their pharmaceutical compositions and to their use in the prevention, reduction or treatment of pain and/or inflammation.

公开(公告)号：EP3868368A1

公开(公告)日：2021-08-25

申请号：EP20158749.0

申请日：2020-02-21

Applicant: Dompe' Farmaceutici S.P.A.

Inventor： RUSSO, Remo de Castro ,  TEIXEIRA, Mauro Martin ,  BRANDOLINI, Laura ,  ALLEGRETTI, Marcello

IPC: A61K31/18 ,  A61K31/00 ,  A61K31/573 ,  A61K45/06 ,  A61P11/06

Abstract: The present invention relates to a combination of a CXCL8 activity inhibitor and a corticosteroid, and a pharmaceutical composition thereof, for use in the treatment of corticosteroid-insensitive asthma as well as to a method for treating corticosteroid-insensitive asthma by administration of said pharmaceutical composition.